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A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.
Holmans P, Moskvina V, Jones L, Sharma M; International Parkinson's Disease Genomics Consortium; Vedernikov A, Buchel F, Saad M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM. Holmans P, et al. Among authors: williams nm. Hum Mol Genet. 2013 Mar 1;22(5):1039-49. doi: 10.1093/hmg/dds492. Epub 2012 Dec 7. Hum Mol Genet. 2013. PMID: 23223016 Free PMC article.
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.
Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV, Brzustowicz LM, Kaufmann CA, Garver DL, Gurling HM, Lindholm E, Coon H, Moises HW, Byerley W, Shaw SH, Mesen A, Sherrington R, O'Neill FA, Walsh D, Kendler KS, Ekelund J, Paunio T, Lönnqvist J, Peltonen L, O'Donovan MC, Owen MJ, Wildenauer DB, Maier W, Nestadt G, Blouin JL, Antonarakis SE, Mowry BJ, Silverman JM, Crowe RR, Cloninger CR, Tsuang MT, Malaspina D, Harkavy-Friedman JM, Svrakic DM, Bassett AS, Holcomb J, Kalsi G, McQuillin A, Brynjolfson J, Sigmundsson T, Petursson H, Jazin E, Zoëga T, Helgason T. Lewis CM, et al. Among authors: williams nm. Am J Hum Genet. 2003 Jul;73(1):34-48. doi: 10.1086/376549. Epub 2003 Jun 11. Am J Hum Genet. 2003. PMID: 12802786 Free PMC article.
Recent advances in the genetics of schizophrenia.
O'Donovan MC, Williams NM, Owen MJ. O'Donovan MC, et al. Among authors: williams nm. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R125-33. doi: 10.1093/hmg/ddg302. Epub 2003 Sep 2. Hum Mol Genet. 2003. PMID: 12952866 Review.
Support for RGS4 as a susceptibility gene for schizophrenia.
Williams NM, Preece A, Spurlock G, Norton N, Williams HJ, McCreadie RG, Buckland P, Sharkey V, Chowdari KV, Zammit S, Nimgaonkar V, Kirov G, Owen MJ, O'Donovan MC. Williams NM, et al. Among authors: williams hj. Biol Psychiatry. 2004 Jan 15;55(2):192-5. doi: 10.1016/j.biopsych.2003.11.002. Biol Psychiatry. 2004. PMID: 14732600
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Glaser B, Schumacher J, Williams HJ, Jamra RA, Ianakiev N, Milev R, Ohlraun S, Schulze TG, Czerski PM, Hauser J, Jönsson EG, Sedvall GC, Klopp N, Illig T, Becker T, Propping P, Williams NM, Cichon S, Kirov G, Rietschel M, Murphy KC, O'Donovan MC, Nöthen MM, Owen MJ. Glaser B, et al. Among authors: williams hj, williams nm. Biol Psychiatry. 2005 Jul 1;58(1):78-80. doi: 10.1016/j.biopsych.2005.03.017. Biol Psychiatry. 2005. PMID: 15992527
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia.
Norton N, Moskvina V, Morris DW, Bray NJ, Zammit S, Williams NM, Williams HJ, Preece AC, Dwyer S, Wilkinson JC, Spurlock G, Kirov G, Buckland P, Waddington JL, Gill M, Corvin AP, Owen MJ, O'Donovan MC. Norton N, et al. Among authors: williams hj, williams nm. Am J Med Genet B Neuropsychiatr Genet. 2006 Jan 5;141B(1):96-101. doi: 10.1002/ajmg.b.30236. Am J Med Genet B Neuropsychiatr Genet. 2006. PMID: 16249994
345 results