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Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis.
Umiċeviċ Mirkov M, Cui J, Vermeulen SH, Stahl EA, Toonen EJ, Makkinje RR, Lee AT, Huizinga TW, Allaart R, Barton A, Mariette X, Miceli CR, Criswell LA, Tak PP, de Vries N, Saevarsdottir S, Padyukov L, Bridges SL, van Schaardenburg DJ, Jansen TL, Dutmer EA, van de Laar MA, Barrera P, Radstake TR, van Riel PL, Scheffer H, Franke B, Brunner HG, Plenge RM, Gregersen PK, Guchelaar HJ, Coenen MJ. Umiċeviċ Mirkov M, et al. Among authors: scheffer h. Ann Rheum Dis. 2013 Aug;72(8):1375-81. doi: 10.1136/annrheumdis-2012-202405. Epub 2012 Dec 11. Ann Rheum Dis. 2013. PMID: 23233654 Free PMC article.
The tumour necrosis factor receptor superfamily member 1b 676T>G polymorphism in relation to response to infliximab and adalimumab treatment and disease severity in rheumatoid arthritis.
Toonen EJ, Coenen MJ, Kievit W, Fransen J, Eijsbouts AM, Scheffer H, Radstake TR, Creemers MC, de Rooij DJ, van Riel PL, Franke B, Barrera P. Toonen EJ, et al. Among authors: scheffer h. Ann Rheum Dis. 2008 Aug;67(8):1174-7. doi: 10.1136/ard.2008.088138. Epub 2008 Apr 2. Ann Rheum Dis. 2008. PMID: 18385279
Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome.
Coenen MJ, Enevold C, Barrera P, Schijvenaars MM, Toonen EJ, Scheffer H, Padyukov L, Kastbom A, Klareskog L, Barton A, Kievit W, Rood MJ, Jansen TL, Swinkels D, van Riel PL, Franke B, Bendtzen K, Radstake TR. Coenen MJ, et al. Among authors: scheffer h. PLoS One. 2010 Dec 15;5(12):e14326. doi: 10.1371/journal.pone.0014326. PLoS One. 2010. PMID: 21179534 Free PMC article.
Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis.
Toonen EJ, Gilissen C, Franke B, Kievit W, Eijsbouts AM, den Broeder AA, van Reijmersdal SV, Veltman JA, Scheffer H, Radstake TR, van Riel PL, Barrera P, Coenen MJ. Toonen EJ, et al. Among authors: scheffer h. PLoS One. 2012;7(3):e33199. doi: 10.1371/journal.pone.0033199. Epub 2012 Mar 21. PLoS One. 2012. PMID: 22457743 Free PMC article.
Early Assessment of Thiopurine Metabolites Identifies Patients at Risk of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease.
Wong DR, Coenen MJ, Vermeulen SH, Derijks LJ, van Marrewijk CJ, Klungel OH, Scheffer H, Franke B, Guchelaar HJ, de Jong DJ, Engels LG, Verbeek AL, Hooymans PM; TOPIC recruitment team. Wong DR, et al. Among authors: scheffer h. J Crohns Colitis. 2017 Feb;11(2):175-184. doi: 10.1093/ecco-jcc/jjw130. Epub 2016 Jul 9. J Crohns Colitis. 2017. PMID: 27402913 Clinical Trial.
Genotype-Guided Thiopurine Dosing Does not Lead to Additional Costs in Patients With Inflammatory Bowel Disease.
Sluiter RL, Van Marrewijk C, De Jong D, Scheffer H, Guchelaar HJ, Derijks L, Wong DR, Hooymans P, Vermeulen SH, Verbeek ALM, Franke B, Van der Wilt GJ, Kievit W, Coenen MJH. Sluiter RL, et al. Among authors: scheffer h. J Crohns Colitis. 2019 Jul 25;13(7):838-845. doi: 10.1093/ecco-jcc/jjz009. J Crohns Colitis. 2019. PMID: 30698675 Free PMC article. Clinical Trial.
Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.
Coenen MJ, de Jong DJ, van Marrewijk CJ, Derijks LJ, Vermeulen SH, Wong DR, Klungel OH, Verbeek AL, Hooymans PM, Peters WH, te Morsche RH, Newman WG, Scheffer H, Guchelaar HJ, Franke B; TOPIC Recruitment Team. Coenen MJ, et al. Among authors: scheffer h. Gastroenterology. 2015 Oct;149(4):907-17.e7. doi: 10.1053/j.gastro.2015.06.002. Epub 2015 Jun 11. Gastroenterology. 2015. PMID: 26072396 Clinical Trial.
315 results