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High-dimensional immunomonitoring models of HIV-1-specific CD8 T-cell responses accurately identify subjects achieving spontaneous viral control.
Ndhlovu ZM, Chibnik LB, Proudfoot J, Vine S, McMullen A, Cesa K, Porichis F, Jones RB, Alvino DM, Hart MG, Stampouloglou E, Piechocka-Trocha A, Kadie C, Pereyra F, Heckerman D, De Jager PL, Walker BD, Kaufmann DE. Ndhlovu ZM, et al. Among authors: jones rb. Blood. 2013 Jan 31;121(5):801-11. doi: 10.1182/blood-2012-06-436295. Epub 2012 Dec 11. Blood. 2013. PMID: 23233659 Free PMC article. Clinical Trial.
HIV-specific CD8⁺ T cells and HIV eradication.
Jones RB, Walker BD. Jones RB, et al. J Clin Invest. 2016 Feb;126(2):455-63. doi: 10.1172/JCI80566. Epub 2016 Jan 5. J Clin Invest. 2016. PMID: 26731469 Free PMC article. Review.
A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes.
Jones RB, Mueller S, O'Connor R, Rimpel K, Sloan DD, Karel D, Wong HC, Jeng EK, Thomas AS, Whitney JB, Lim SY, Kovacs C, Benko E, Karandish S, Huang SH, Buzon MJ, Lichterfeld M, Irrinki A, Murry JP, Tsai A, Yu H, Geleziunas R, Trocha A, Ostrowski MA, Irvine DJ, Walker BD. Jones RB, et al. PLoS Pathog. 2016 Apr 15;12(4):e1005545. doi: 10.1371/journal.ppat.1005545. eCollection 2016 Apr. PLoS Pathog. 2016. PMID: 27082643 Free PMC article.
Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.
Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB, Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, Crawford F, White J, Montoya A, Power K, Allen TM, Streeck H, Kaufmann DE, Picker LJ, Kappler JW, Walker BD. Ranasinghe S, et al. Among authors: jones rb. Immunity. 2016 Oct 18;45(4):917-930. doi: 10.1016/j.immuni.2016.09.015. Immunity. 2016. PMID: 27760342 Free PMC article.
T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
Thomas AS, Jones KL, Gandhi RT, McMahon DK, Cyktor JC, Chan D, Huang SH, Truong R, Bosque A, Macedo AB, Kovacs C, Benko E, Eron JJ, Bosch RJ, Lalama CM, Simmens S, Walker BD, Mellors JW, Jones RB. Thomas AS, et al. Among authors: jones rb, jones kl. PLoS Pathog. 2017 Sep 20;13(9):e1006629. doi: 10.1371/journal.ppat.1006629. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28931091 Free PMC article.
Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.
Huang SH, Ren Y, Thomas AS, Chan D, Mueller S, Ward AR, Patel S, Bollard CM, Cruz CR, Karandish S, Truong R, Macedo AB, Bosque A, Kovacs C, Benko E, Piechocka-Trocha A, Wong H, Jeng E, Nixon DF, Ho YC, Siliciano RF, Walker BD, Jones RB. Huang SH, et al. Among authors: jones rb. J Clin Invest. 2018 Feb 1;128(2):876-889. doi: 10.1172/JCI97555. Epub 2018 Jan 22. J Clin Invest. 2018. PMID: 29355843 Free PMC article.
The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles.
Webb GM, Li S, Mwakalundwa G, Folkvord JM, Greene JM, Reed JS, Stanton JJ, Legasse AW, Hobbs T, Martin LD, Park BS, Whitney JB, Jeng EK, Wong HC, Nixon DF, Jones RB, Connick E, Skinner PJ, Sacha JB. Webb GM, et al. Among authors: jones rb. Blood Adv. 2018 Jan 23;2(2):76-84. doi: 10.1182/bloodadvances.2017012971. Blood Adv. 2018. PMID: 29365313 Free PMC article.
865 results