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DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila.
Fisher WW, Li JJ, Hammonds AS, Brown JB, Pfeiffer BD, Weiszmann R, MacArthur S, Thomas S, Stamatoyannopoulos JA, Eisen MB, Bickel PJ, Biggin MD, Celniker SE. Fisher WW, et al. Among authors: biggin md. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21330-5. doi: 10.1073/pnas.1209589110. Epub 2012 Dec 10. Proc Natl Acad Sci U S A. 2012. PMID: 23236164 Free PMC article.
Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.
Li XY, MacArthur S, Bourgon R, Nix D, Pollard DA, Iyer VN, Hechmer A, Simirenko L, Stapleton M, Luengo Hendriks CL, Chu HC, Ogawa N, Inwood W, Sementchenko V, Beaton A, Weiszmann R, Celniker SE, Knowles DW, Gingeras T, Speed TP, Eisen MB, Biggin MD. Li XY, et al. Among authors: biggin md. PLoS Biol. 2008 Feb;6(2):e27. doi: 10.1371/journal.pbio.0060027. PLoS Biol. 2008. PMID: 18271625 Free PMC article.
A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm.
Fowlkes CC, Hendriks CL, Keränen SV, Weber GH, Rübel O, Huang MY, Chatoor S, DePace AH, Simirenko L, Henriquez C, Beaton A, Weiszmann R, Celniker S, Hamann B, Knowles DW, Biggin MD, Eisen MB, Malik J. Fowlkes CC, et al. Among authors: biggin md. Cell. 2008 Apr 18;133(2):364-74. doi: 10.1016/j.cell.2008.01.053. Cell. 2008. PMID: 18423206 Free article.
Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions.
MacArthur S, Li XY, Li J, Brown JB, Chu HC, Zeng L, Grondona BP, Hechmer A, Simirenko L, Keränen SV, Knowles DW, Stapleton M, Bickel P, Biggin MD, Eisen MB. MacArthur S, et al. Among authors: biggin md. Genome Biol. 2009;10(7):R80. doi: 10.1186/gb-2009-10-7-r80. Epub 2009 Jul 23. Genome Biol. 2009. PMID: 19627575 Free PMC article.
Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy.
Arbel H, Basu S, Fisher WW, Hammonds AS, Wan KH, Park S, Weiszmann R, Booth BW, Keranen SV, Henriquez C, Shams Solari O, Bickel PJ, Biggin MD, Celniker SE, Brown JB. Arbel H, et al. Among authors: biggin md. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):900-908. doi: 10.1073/pnas.1808833115. Epub 2018 Dec 31. Proc Natl Acad Sci U S A. 2019. PMID: 30598455 Free PMC article.
Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline.
Luengo Hendriks CL, Keränen SV, Fowlkes CC, Simirenko L, Weber GH, DePace AH, Henriquez C, Kaszuba DW, Hamann B, Eisen MB, Malik J, Sudar D, Biggin MD, Knowles DW. Luengo Hendriks CL, et al. Among authors: biggin md. Genome Biol. 2006;7(12):R123. doi: 10.1186/gb-2006-7-12-r123. Genome Biol. 2006. PMID: 17184546 Free PMC article.
75 results