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Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium.
Mäkelä KM, Seppälä I, Hernesniemi JA, Lyytikäinen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kähönen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjärvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JS, Kähönen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, März W, Lehtimäki T. Mäkelä KM, et al. Among authors: seppala i. Circ Cardiovasc Genet. 2013 Feb;6(1):73-81. doi: 10.1161/CIRCGENETICS.112.964965. Epub 2012 Dec 17. Circ Cardiovasc Genet. 2013. PMID: 23247145
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.
Hernesniemi JA, Seppälä I, Lyytikäinen LP, Mononen N, Oksala N, Hutri-Kähönen N, Juonala M, Taittonen L, Smith EN, Schork NJ, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, Jula A, Kettunen J, Ripatti S, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Hernesniemi JA, et al. Among authors: seppala i. PLoS One. 2012;7(1):e28931. doi: 10.1371/journal.pone.0028931. Epub 2012 Jan 25. PLoS One. 2012. PMID: 22295058 Free PMC article.
Childhood physical, environmental, and genetic predictors of adult hypertension: the cardiovascular risk in young Finns study.
Juhola J, Oikonen M, Magnussen CG, Mikkilä V, Siitonen N, Jokinen E, Laitinen T, Würtz P, Gidding SS, Taittonen L, Seppälä I, Jula A, Kähönen M, Hutri-Kähönen N, Lehtimäki T, Viikari JS, Juonala M, Raitakari OT. Juhola J, et al. Among authors: seppala i. Circulation. 2012 Jul 24;126(4):402-9. doi: 10.1161/CIRCULATIONAHA.111.085977. Epub 2012 Jun 20. Circulation. 2012. PMID: 22718800
Genome-wide association study identifies 3 genomic loci significantly associated with serum levels of homoarginine: the AtheroRemo Consortium.
Kleber ME, Seppälä I, Pilz S, Hoffmann MM, Tomaschitz A, Oksala N, Raitoharju E, Lyytikäinen LP, Mäkelä KM, Laaksonen R, Kähönen M, Raitakari OT, Huang J, Kienreich K, Fahrleitner-Pammer A, Drechsler C, Krane V, Boehm BO, Koenig W, Wanner C, Lehtimäki T, März W, Meinitzer A. Kleber ME, et al. Among authors: seppala i. Circ Cardiovasc Genet. 2013 Oct;6(5):505-13. doi: 10.1161/CIRCGENETICS.113.000108. Epub 2013 Sep 18. Circ Cardiovasc Genet. 2013. PMID: 24047826
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
Seppälä I, Kleber ME, Lyytikäinen LP, Hernesniemi JA, Mäkelä KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kähönen N, Alfthan G, Viikari JS, Kähonen M, Raitakari OT, März W, Meinitzer A, Lehtimäki T; AtheroRemo Consortium. Seppälä I, et al. Eur Heart J. 2014 Feb;35(8):524-31. doi: 10.1093/eurheartj/eht447. Epub 2013 Oct 24. Eur Heart J. 2014. PMID: 24159190 Free article.
Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events.
Mäkelä KM, Traylor M, Oksala N, Kleber ME, Seppälä I, Lyytikäinen LP, Hernesniemi JA, Kähönen M, Bevan S, Rothwell PM, Sudlow C, Dichgans M; Wellcome Trust Case Control Consortium 2 (WTCCC2); Delgado G, Grammer TB, Scharnagl H, Markus HS, März W, Lehtimäki T. Mäkelä KM, et al. Among authors: seppala i. Atherosclerosis. 2014 May;234(1):214-7. doi: 10.1016/j.atherosclerosis.2014.03.002. Epub 2014 Mar 14. Atherosclerosis. 2014. PMID: 24681816
A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.
Turpeinen H, Seppälä I, Lyytikäinen LP, Raitoharju E, Hutri-Kähönen N, Levula M, Oksala N, Waldenberger M, Klopp N, Illig T, Mononen N, Laaksonen R, Raitakari O, Kähönen M, Lehtimäki T, Pesu M. Turpeinen H, et al. Among authors: seppala i. Hum Genet. 2015 Jun;134(6):627-36. doi: 10.1007/s00439-015-1546-5. Epub 2015 Mar 27. Hum Genet. 2015. PMID: 25813623 Clinical Trial.
Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts.
Raitoharju E, Seppälä I, Levula M, Kuukasjärvi P, Laurikka J, Nikus K, Huovila AP, Oksala N, Klopp N, Illig T, Laaksonen R, Karhunen PJ, Viik J, Lehtinen R, Pelto-Huikko M, Tarkka M, Kähönen M, Lehtimäki T. Raitoharju E, et al. Among authors: seppala i. Atherosclerosis. 2011 Sep;218(1):127-33. doi: 10.1016/j.atherosclerosis.2011.05.005. Epub 2011 May 13. Atherosclerosis. 2011. PMID: 21640993
240 results