Parkinson G - Search Results

1

C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.

Fratta P, Mizielinska S, Nicoll AJ, Zloh M, Fisher EM, Parkinson G, Isaacs AM. Fratta P, et al. Among authors: parkinson g. Sci Rep. 2012;2:1016. doi: 10.1038/srep01016. Epub 2012 Dec 21. Sci Rep. 2012. PMID: 23264878 Free PMC article.

2

Putative DNA quadruplex formation within the human c-kit oncogene.

Rankin S, Reszka AP, Huppert J, Zloh M, Parkinson GN, Todd AK, Ladame S, Balasubramanian S, Neidle S. Rankin S, et al. J Am Chem Soc. 2005 Aug 3;127(30):10584-9. doi: 10.1021/ja050823u. J Am Chem Soc. 2005. PMID: 16045346 Free PMC article.

3

Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.

Antonow D, Barata T, Jenkins TC, Parkinson GN, Howard PW, Thurston DE, Zloh M. Antonow D, et al. Biochemistry. 2008 Nov 11;47(45):11818-29. doi: 10.1021/bi801225q. Epub 2008 Oct 17. Biochemistry. 2008. PMID: 18925745

4

Selectivity in small molecule binding to human telomeric RNA and DNA quadruplexes.

Collie G, Reszka AP, Haider SM, Gabelica V, Parkinson GN, Neidle S. Collie G, et al. Among authors: parkinson gn. Chem Commun (Camb). 2009 Dec 28;(48):7482-4. doi: 10.1039/b901889a. Epub 2009 Nov 13. Chem Commun (Camb). 2009. PMID: 20024253 Free article.

5

The application of DNA and RNA G-quadruplexes to therapeutic medicines.

Collie GW, Parkinson GN. Collie GW, et al. Chem Soc Rev. 2011 Dec;40(12):5867-92. doi: 10.1039/c1cs15067g. Epub 2011 Jul 25. Chem Soc Rev. 2011. PMID: 21789296 Review.

6

Crystal structure of a promoter sequence in the B-raf gene reveals an intertwined dimer quadruplex.

Wei D, Todd AK, Zloh M, Gunaratnam M, Parkinson GN, Neidle S. Wei D, et al. J Am Chem Soc. 2013 Dec 26;135(51):19319-29. doi: 10.1021/ja4101358. Epub 2013 Dec 11. J Am Chem Soc. 2013. PMID: 24295054

7

G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome.

Simone R, Fratta P, Neidle S, Parkinson GN, Isaacs AM. Simone R, et al. FEBS Lett. 2015 Jun 22;589(14):1653-68. doi: 10.1016/j.febslet.2015.05.003. Epub 2015 May 13. FEBS Lett. 2015. PMID: 25979174 Free article. Review.

8

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.

Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, Calvo A, Chio A, Houlden H, Polke JM, Ismail MA, Stephens CE, Vo T, Farahat AA, Wilson WD, Boykin DW, Zetterberg H, Partridge L, Wray S, Parkinson G, Neidle S, Patani R, Fratta P, Isaacs AM. Simone R, et al. Among authors: parkinson g. EMBO Mol Med. 2018 Jan;10(1):22-31. doi: 10.15252/emmm.201707850. EMBO Mol Med. 2018. PMID: 29113975 Free PMC article.

9

Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures.

Hazel P, Parkinson GN, Neidle S. Hazel P, et al. Nucleic Acids Res. 2006 Apr 26;34(7):2117-27. doi: 10.1093/nar/gkl182. Print 2006. Nucleic Acids Res. 2006. PMID: 16641317 Free PMC article.

10

Quadruplex DNA: sequence, topology and structure.

Burge S, Parkinson GN, Hazel P, Todd AK, Neidle S. Burge S, et al. Nucleic Acids Res. 2006;34(19):5402-15. doi: 10.1093/nar/gkl655. Epub 2006 Sep 29. Nucleic Acids Res. 2006. PMID: 17012276 Free PMC article. Review.

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