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314 results

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Imbalance of Hsp70 family variants fosters tau accumulation.
Jinwal UK, Akoury E, Abisambra JF, O'Leary JC 3rd, Thompson AD, Blair LJ, Jin Y, Bacon J, Nordhues BA, Cockman M, Zhang J, Li P, Zhang B, Borysov S, Uversky VN, Biernat J, Mandelkow E, Gestwicki JE, Zweckstetter M, Dickey CA. Jinwal UK, et al. Among authors: biernat j. FASEB J. 2013 Apr;27(4):1450-9. doi: 10.1096/fj.12-220889. Epub 2012 Dec 27. FASEB J. 2013. PMID: 23271055 Free PMC article.
Hsp90-Tau complex reveals molecular basis for specificity in chaperone action.
Karagöz GE, Duarte AM, Akoury E, Ippel H, Biernat J, Morán Luengo T, Radli M, Didenko T, Nordhues BA, Veprintsev DB, Dickey CA, Mandelkow E, Zweckstetter M, Boelens R, Madl T, Rüdiger SG. Karagöz GE, et al. Among authors: biernat j. Cell. 2014 Feb 27;156(5):963-74. doi: 10.1016/j.cell.2014.01.037. Cell. 2014. PMID: 24581495 Free PMC article.
Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.
Oroz J, Chang BJ, Wysoczanski P, Lee CT, Pérez-Lara Á, Chakraborty P, Hofele RV, Baker JD, Blair LJ, Biernat J, Urlaub H, Mandelkow E, Dickey CA, Zweckstetter M. Oroz J, et al. Among authors: biernat j. Nat Commun. 2018 Oct 31;9(1):4532. doi: 10.1038/s41467-018-06880-0. Nat Commun. 2018. PMID: 30382094 Free PMC article.
Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation.
Akoury E, Pickhardt M, Gajda M, Biernat J, Mandelkow E, Zweckstetter M. Akoury E, et al. Among authors: biernat j. Angew Chem Int Ed Engl. 2013 Mar 18;52(12):3511-5. doi: 10.1002/anie.201208290. Epub 2013 Feb 11. Angew Chem Int Ed Engl. 2013. PMID: 23401175 No abstract available.
The "jaws" of the tau-microtubule interaction.
Mukrasch MD, von Bergen M, Biernat J, Fischer D, Griesinger C, Mandelkow E, Zweckstetter M. Mukrasch MD, et al. Among authors: biernat j. J Biol Chem. 2007 Apr 20;282(16):12230-9. doi: 10.1074/jbc.M607159200. Epub 2007 Feb 15. J Biol Chem. 2007. PMID: 17307736 Free article.
The dynamic structure of filamentous tau.
Bibow S, Mukrasch MD, Chinnathambi S, Biernat J, Griesinger C, Mandelkow E, Zweckstetter M. Bibow S, et al. Among authors: biernat j. Angew Chem Int Ed Engl. 2011 Nov 25;50(48):11520-4. doi: 10.1002/anie.201105493. Epub 2011 Oct 11. Angew Chem Int Ed Engl. 2011. PMID: 21990182 No abstract available.
Inhibition of tau filament formation by conformational modulation.
Akoury E, Gajda M, Pickhardt M, Biernat J, Soraya P, Griesinger C, Mandelkow E, Zweckstetter M. Akoury E, et al. Among authors: biernat j. J Am Chem Soc. 2013 Feb 20;135(7):2853-62. doi: 10.1021/ja312471h. Epub 2013 Feb 5. J Am Chem Soc. 2013. PMID: 23360400 Free article.
314 results