Borysov S - Search Results

1

Imbalance of Hsp70 family variants fosters tau accumulation.

Jinwal UK, Akoury E, Abisambra JF, O'Leary JC 3rd, Thompson AD, Blair LJ, Jin Y, Bacon J, Nordhues BA, Cockman M, Zhang J, Li P, Zhang B, Borysov S, Uversky VN, Biernat J, Mandelkow E, Gestwicki JE, Zweckstetter M, Dickey CA. Jinwal UK, et al. Among authors: borysov s. FASEB J. 2013 Apr;27(4):1450-9. doi: 10.1096/fj.12-220889. Epub 2012 Dec 27. FASEB J. 2013. PMID: 23271055 Free PMC article.

2

The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics.

Fontaine SN, Martin MD, Akoury E, Assimon VA, Borysov S, Nordhues BA, Sabbagh JJ, Cockman M, Gestwicki JE, Zweckstetter M, Dickey CA. Fontaine SN, et al. Among authors: borysov s. Hum Mol Genet. 2015 Jul 15;24(14):3971-81. doi: 10.1093/hmg/ddv135. Epub 2015 Apr 16. Hum Mol Genet. 2015. PMID: 25882706 Free PMC article.

3

The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

Jinwal UK, Koren J 3rd, Borysov SI, Schmid AB, Abisambra JF, Blair LJ, Johnson AG, Jones JR, Shults CL, O'Leary JC 3rd, Jin Y, Buchner J, Cox MB, Dickey CA. Jinwal UK, et al. J Neurosci. 2010 Jan 13;30(2):591-9. doi: 10.1523/JNEUROSCI.4815-09.2010. J Neurosci. 2010. PMID: 20071522 Free PMC article.

4

Hsc70 rapidly engages tau after microtubule destabilization.

Jinwal UK, O'Leary JC 3rd, Borysov SI, Jones JR, Li Q, Koren J 3rd, Abisambra JF, Vestal GD, Lawson LY, Johnson AG, Blair LJ, Jin Y, Miyata Y, Gestwicki JE, Dickey CA. Jinwal UK, et al. J Biol Chem. 2010 May 28;285(22):16798-805. doi: 10.1074/jbc.M110.113753. Epub 2010 Mar 22. J Biol Chem. 2010. PMID: 20308058 Free PMC article.

5

Alzheimer Aβ disrupts the mitotic spindle and directly inhibits mitotic microtubule motors.

Borysov SI, Granic A, Padmanabhan J, Walczak CE, Potter H. Borysov SI, et al. Cell Cycle. 2011 May 1;10(9):1397-410. doi: 10.4161/cc.10.9.15478. Epub 2011 May 1. Cell Cycle. 2011. PMID: 21566458 Free PMC article.

6

Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function.

Ari C, Borysov SI, Wu J, Padmanabhan J, Potter H. Ari C, et al. Neurobiol Aging. 2014 Aug;35(8):1839-49. doi: 10.1016/j.neurobiolaging.2014.02.006. Epub 2014 Feb 10. Neurobiol Aging. 2014. PMID: 24636920 Free PMC article.

7

B-Raf is critical for MAPK activation during mitosis and is regulated in an M phase-dependent manner in Xenopus egg extracts.

Borysov SI, Cheng AW, Guadagno TM. Borysov SI, et al. J Biol Chem. 2006 Aug 11;281(32):22586-96. doi: 10.1074/jbc.M601432200. Epub 2006 Jun 8. J Biol Chem. 2006. PMID: 16762920 Free article.

8

Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders.

Potter H, Chial HJ, Caneus J, Elos M, Elder N, Borysov S, Granic A. Potter H, et al. Among authors: borysov s. Front Genet. 2019 Nov 7;10:1092. doi: 10.3389/fgene.2019.01092. eCollection 2019. Front Genet. 2019. PMID: 31788001 Free PMC article.

9

A novel role for Cdk1/cyclin B in regulating B-raf activation at mitosis.

Borysov SI, Guadagno TM. Borysov SI, et al. Mol Biol Cell. 2008 Jul;19(7):2907-15. doi: 10.1091/mbc.e07-07-0679. Epub 2008 Apr 23. Mol Biol Cell. 2008. PMID: 18434602 Free PMC article.

10

Analysis of DNA replication associated chromatin decondensation: in vivo assay for understanding chromatin remodeling mechanisms of selected proteins.

Borysov S, Bryant VL, Alexandrow MG. Borysov S, et al. Methods Mol Biol. 2015;1288:289-303. doi: 10.1007/978-1-4939-2474-5_16. Methods Mol Biol. 2015. PMID: 25827886

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