Thompson AD - Search Results

1

Imbalance of Hsp70 family variants fosters tau accumulation.

Jinwal UK, Akoury E, Abisambra JF, O'Leary JC 3rd, Thompson AD, Blair LJ, Jin Y, Bacon J, Nordhues BA, Cockman M, Zhang J, Li P, Zhang B, Borysov S, Uversky VN, Biernat J, Mandelkow E, Gestwicki JE, Zweckstetter M, Dickey CA. Jinwal UK, et al. Among authors: thompson ad. FASEB J. 2013 Apr;27(4):1450-9. doi: 10.1096/fj.12-220889. Epub 2012 Dec 27. FASEB J. 2013. PMID: 23271055 Free PMC article.

2

Mutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK).

Chang L, Thompson AD, Ung P, Carlson HA, Gestwicki JE. Chang L, et al. Among authors: thompson ad. J Biol Chem. 2010 Jul 9;285(28):21282-91. doi: 10.1074/jbc.M110.124149. Epub 2010 May 3. J Biol Chem. 2010. PMID: 20439464 Free PMC article.

3

Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.

Wisén S, Bertelsen EB, Thompson AD, Patury S, Ung P, Chang L, Evans CG, Walter GM, Wipf P, Carlson HA, Brodsky JL, Zuiderweg ER, Gestwicki JE. Wisén S, et al. Among authors: thompson ad. ACS Chem Biol. 2010 Jun 18;5(6):611-22. doi: 10.1021/cb1000422. ACS Chem Biol. 2010. PMID: 20481474 Free PMC article.

4

Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK).

Thompson AD, Bernard SM, Skiniotis G, Gestwicki JE. Thompson AD, et al. Cell Stress Chaperones. 2012 May;17(3):313-27. doi: 10.1007/s12192-011-0307-1. Epub 2011 Nov 11. Cell Stress Chaperones. 2012. PMID: 22076723 Free PMC article.

5

The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools.

Thompson AD, Makley LN, McMenimen K, Gestwicki JE. Thompson AD, et al. ACS Chem Biol. 2012 May 18;7(5):791-6. doi: 10.1021/cb3001827. ACS Chem Biol. 2012. PMID: 22594530 No abstract available.

6

Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation.

Chafekar SM, Wisén S, Thompson AD, Echeverria A, Walter GM, Evans CG, Makley LN, Gestwicki JE, Duennwald ML. Chafekar SM, et al. Among authors: thompson ad. ACS Chem Biol. 2012 Sep 21;7(9):1556-64. doi: 10.1021/cb300166p. Epub 2012 Jun 22. ACS Chem Biol. 2012. PMID: 22709427 Free PMC article.

7

Fine-tuning multiprotein complexes using small molecules.

Thompson AD, Dugan A, Gestwicki JE, Mapp AK. Thompson AD, et al. ACS Chem Biol. 2012 Aug 17;7(8):1311-20. doi: 10.1021/cb300255p. Epub 2012 Jul 23. ACS Chem Biol. 2012. PMID: 22725693 Free PMC article. Review.

8

Molecular chaperones DnaK and DnaJ share predicted binding sites on most proteins in the E. coli proteome.

Srinivasan SR, Gillies AT, Chang L, Thompson AD, Gestwicki JE. Srinivasan SR, et al. Among authors: thompson ad. Mol Biosyst. 2012 Sep;8(9):2323-33. doi: 10.1039/c2mb25145k. Epub 2012 Jun 25. Mol Biosyst. 2012. PMID: 22732719 Free PMC article.

9

Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation.

Thompson AD, Scaglione KM, Prensner J, Gillies AT, Chinnaiyan A, Paulson HL, Jinwal UK, Dickey CA, Gestwicki JE. Thompson AD, et al. ACS Chem Biol. 2012 Oct 19;7(10):1677-86. doi: 10.1021/cb3002599. Epub 2012 Jul 25. ACS Chem Biol. 2012. PMID: 22769591 Free PMC article.

10

Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70.

Miyata Y, Rauch JN, Jinwal UK, Thompson AD, Srinivasan S, Dickey CA, Gestwicki JE. Miyata Y, et al. Among authors: thompson ad. Chem Biol. 2012 Nov 21;19(11):1391-9. doi: 10.1016/j.chembiol.2012.07.026. Chem Biol. 2012. PMID: 23177194 Free PMC article.

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