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Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans.
PLoS One. 2012;7(12):e53049. doi: 10.1371/journal.pone.0053049. Epub 2012 Dec 28.
PLoS One. 2012.
PMID: 23285254
Free PMC article.
Balancing immunity and tolerance: genetic footprint of natural selection in the transcriptional regulatory region of HLA-G.
Gineau L, Luisi P, Castelli EC, Milet J, Courtin D, Cagnin N, Patillon B, Laayouni H, Moreau P, Donadi EA, Garcia A, Sabbagh A.
Gineau L, et al. Among authors: patillon b.
Genes Immun. 2015 Jan-Feb;16(1):57-70. doi: 10.1038/gene.2014.63. Epub 2014 Nov 13.
Genes Immun. 2015.
PMID: 25393930
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A homogenizing process of selection has maintained an "ultra-slow" acetylation NAT2 variant in humans.
Patillon B, Luisi P, Poloni ES, Boukouvala S, Darlu P, Genin E, Sabbagh A.
Patillon B, et al.
Hum Biol. 2014 Summer;86(3):185-214. doi: 10.13110/humanbiology.86.3.0185.
Hum Biol. 2014.
PMID: 25836746
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MDM2 as a modifier gene in retinoblastoma.
Castéra L, Sabbagh A, Dehainault C, Michaux D, Mansuet-Lupo A, Patillon B, Lamar E, Aerts I, Lumbroso-Le Rouic L, Couturier J, Stoppa-Lyonnet D, Gauthier-Villars M, Houdayer C.
Castéra L, et al. Among authors: patillon b.
J Natl Cancer Inst. 2010 Dec 1;102(23):1805-8. doi: 10.1093/jnci/djq416. Epub 2010 Nov 4.
J Natl Cancer Inst. 2010.
PMID: 21051655
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