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Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists.
Richter HG, Adams DR, Benardeau A, Bickerdike MJ, Bentley JM, Blench TJ, Cliffe IA, Dourish C, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Monck NJ, Plancher JM, Roever S, Roffey JR, Taylor S, Vickers SP. Richter HG, et al. Among authors: bentley jm. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1207-11. doi: 10.1016/j.bmcl.2005.11.083. Epub 2005 Dec 19. Bioorg Med Chem Lett. 2006. PMID: 16361098
Pyrrolo(iso)quinoline derivatives as 5-HT(2C) receptor agonists.
Adams DR, Bentley JM, Benwell KR, Bickerdike MJ, Bodkin CD, Cliffe IA, Dourish CT, George AR, Kennett GA, Knight AR, Malcolm CS, Mansell HL, Misra A, Quirk K, Roffey JR, Vickers SP. Adams DR, et al. Among authors: bentley jm. Bioorg Med Chem Lett. 2006 Feb;16(3):677-80. doi: 10.1016/j.bmcl.2005.10.029. Epub 2005 Oct 27. Bioorg Med Chem Lett. 2006. PMID: 16257207
Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists.
Röver S, Adams DR, Bénardeau A, Bentley JM, Bickerdike MJ, Bourson A, Cliffe IA, Coassolo P, Davidson JE, Dourish CT, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Muller M, Porter RH, Richter H, Taylor S, Vickers SP. Röver S, et al. Among authors: bentley jm. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3604-8. doi: 10.1016/j.bmcl.2005.05.074. Bioorg Med Chem Lett. 2005. PMID: 15975787
39 results