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Etravirine in CSF is highly protein bound.
Nguyen A, Rossi S, Croteau D, Best BM, Clifford D, Collier AC, Gelman B, Marra C, McArthur J, McCutchan JA, Morgello S, Simpson D, Ellis RJ, Grant I, Capparelli E, Letendre S; CHARTER Group. Nguyen A, et al. Among authors: mcarthur j. J Antimicrob Chemother. 2013 May;68(5):1161-8. doi: 10.1093/jac/dks517. Epub 2013 Jan 20. J Antimicrob Chemother. 2013. PMID: 23335197 Free PMC article.
Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration.
Croteau D, Rossi SS, Best BM, Capparelli E, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Grant I, Letendre S; CHARTER Group. Croteau D, et al. Among authors: mcarthur j. J Antimicrob Chemother. 2013 Mar;68(3):684-9. doi: 10.1093/jac/dks441. Epub 2012 Nov 9. J Antimicrob Chemother. 2013. PMID: 23143899 Free PMC article.
Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study.
Livelli A, Vaida F, Ellis RJ, Ma Q, Ferrara M, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, McCutchan JA, Morgello S, Sacktor N, Simpson DM, Grant I, Letendre SL; CHARTER Group. Livelli A, et al. Among authors: mcarthur jc. Lancet HIV. 2019 Jul;6(7):e456-e462. doi: 10.1016/S2352-3018(19)30143-2. Epub 2019 Jun 14. Lancet HIV. 2019. PMID: 31208949
Brain morphometric correlates of metabolic variables in HIV: the CHARTER study.
Archibald SL, McCutchan JA, Sanders C, Wolfson T, Jernigan TL, Ellis RJ, Ances BM, Collier AC, McArthur JC, Morgello S, Simpson DM, Marra C, Gelman BB, Clifford DB, Grant I, Fennema-Notestine C; CHARTER Group. Archibald SL, et al. Among authors: mcarthur jc. J Neurovirol. 2014 Dec;20(6):603-11. doi: 10.1007/s13365-014-0284-0. Epub 2014 Sep 17. J Neurovirol. 2014. PMID: 25227933 Free PMC article.
Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change.
Cysique LA, Franklin D Jr, Abramson I, Ellis RJ, Letendre S, Collier A, Clifford D, Gelman B, McArthur J, Morgello S, Simpson D, McCutchan JA, Grant I, Heaton RK; CHARTER Group; HNRC Group. Cysique LA, et al. Among authors: mcarthur j. J Clin Exp Neuropsychol. 2011 Jun;33(5):505-22. doi: 10.1080/13803395.2010.535504. Epub 2011 Mar 7. J Clin Exp Neuropsychol. 2011. PMID: 21391011 Free PMC article.
Continued high prevalence and adverse clinical impact of human immunodeficiency virus-associated sensory neuropathy in the era of combination antiretroviral therapy: the CHARTER Study.
Ellis RJ, Rosario D, Clifford DB, McArthur JC, Simpson D, Alexander T, Gelman BB, Vaida F, Collier A, Marra CM, Ances B, Atkinson JH, Dworkin RH, Morgello S, Grant I; CHARTER Study Group. Ellis RJ, et al. Among authors: mcarthur jc. Arch Neurol. 2010 May;67(5):552-8. doi: 10.1001/archneurol.2010.76. Arch Neurol. 2010. PMID: 20457954 Free PMC article.
HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study.
Heaton RK, Clifford DB, Franklin DR Jr, Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I; CHARTER Group. Heaton RK, et al. Among authors: mcarthur jc. Neurology. 2010 Dec 7;75(23):2087-96. doi: 10.1212/WNL.0b013e318200d727. Neurology. 2010. PMID: 21135382 Free PMC article.
Diagnosing symptomatic HIV-associated neurocognitive disorders: self-report versus performance-based assessment of everyday functioning.
Blackstone K, Moore DJ, Heaton RK, Franklin DR Jr, Woods SP, Clifford DB, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, Rivera-Mindt M, Deutsch R, Ellis RJ, Hampton Atkinson J, Grant I; CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Group. Blackstone K, et al. Among authors: mcarthur jc. J Int Neuropsychol Soc. 2012 Jan;18(1):79-88. doi: 10.1017/S135561771100141X. Epub 2011 Nov 24. J Int Neuropsychol Soc. 2012. PMID: 22114912 Free PMC article.
999 results