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A dose-escalation study of bi-daily once weekly oral docetaxel either as ModraDoc001 or ModraDoc006 combined with ritonavir.
de Weger VA, Stuurman FE, Hendrikx JJMA, Moes JJ, Sawicki E, Huitema ADR, Nuijen B, Thijssen B, Rosing H, Keessen M, Mergui-Roelvink M, Beijnen JH, Schellens JHM, Marchetti S. de Weger VA, et al. Among authors: stuurman fe. Eur J Cancer. 2017 Nov;86:217-225. doi: 10.1016/j.ejca.2017.09.010. Epub 2017 Oct 12. Eur J Cancer. 2017. PMID: 29031170 Clinical Trial.
A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.
de Weger VA, Stuurman FE, Koolen SLW, Moes JJ, Hendrikx JJMA, Sawicki E, Thijssen B, Keessen M, Rosing H, Mergui-Roelvink M, Huitema ADR, Nuijen B, Beijnen JH, Schellens JHM, Marchetti S. de Weger VA, et al. Among authors: stuurman fe. Clin Cancer Res. 2019 Sep 15;25(18):5466-5474. doi: 10.1158/1078-0432.CCR-17-2299. Epub 2019 Jun 19. Clin Cancer Res. 2019. PMID: 31217201 Clinical Trial.
No relation between docetaxel administration route and high-grade diarrhea incidence.
Hendrikx JJMA, Stuurman FE, Song JY, de Weger VA, Lagas JS, Rosing H, Beijnen JH, Schinkel AH, Schellens JHM, Marchetti S. Hendrikx JJMA, et al. Among authors: stuurman fe. Pharmacol Res Perspect. 2020 Aug;8(4):e00633. doi: 10.1002/prp2.633. Pharmacol Res Perspect. 2020. PMID: 32725720 Free PMC article. Clinical Trial.
A Phase 1 Dose-Escalation Study of Low-Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.
de Weger VA, Vermunt MAC, Stuurman FE, Burylo AM, Damoiseaux D, Hendrikx JJMA, Sawicki E, Moes JJ, Huitema ADR, Nuijen B, Rosing H, Mergui-Roelvink M, Beijnen JH, Marchetti S. de Weger VA, et al. Among authors: stuurman fe. Clin Pharmacol Drug Dev. 2021 Jun;10(6):607-621. doi: 10.1002/cpdd.880. Epub 2020 Oct 5. Clin Pharmacol Drug Dev. 2021. PMID: 33021083 Clinical Trial.
An exploratory first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone at a 2- and 1-week interval in patients with metastatic castration resistant prostate cancer.
Vrouwe JPM, Kamerling IMC, van Esdonk MJ, Metselaar JM, Stuurman FE, van der Pluijm G, Burggraaf J, Osanto S. Vrouwe JPM, et al. Among authors: stuurman fe. Pharmacol Res Perspect. 2021 Oct;9(5):e00845. doi: 10.1002/prp2.845. Pharmacol Res Perspect. 2021. PMID: 34414692 Free PMC article.
37 results