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A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.
Nguyen GH, Dexheimer TS, Rosenthal AS, Chu WK, Singh DK, Mosedale G, Bachrati CZ, Schultz L, Sakurai M, Savitsky P, Abu M, McHugh PJ, Bohr VA, Harris CC, Jadhav A, Gileadi O, Maloney DJ, Simeonov A, Hickson ID. Nguyen GH, et al. Among authors: gileadi o. Chem Biol. 2013 Jan 24;20(1):55-62. doi: 10.1016/j.chembiol.2012.10.016. Chem Biol. 2013. PMID: 23352139 Free PMC article.
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
Sengerová B, Allerston CK, Abu M, Lee SY, Hartley J, Kiakos K, Schofield CJ, Hartley JA, Gileadi O, McHugh PJ. Sengerová B, et al. Among authors: gileadi o. J Biol Chem. 2012 Jul 27;287(31):26254-67. doi: 10.1074/jbc.M112.367243. Epub 2012 Jun 11. J Biol Chem. 2012. PMID: 22692201 Free PMC article.
CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.
Iyama T, Lee SY, Berquist BR, Gileadi O, Bohr VA, Seidman MM, McHugh PJ, Wilson DM 3rd. Iyama T, et al. Among authors: gileadi o. Nucleic Acids Res. 2015 Jan;43(1):247-58. doi: 10.1093/nar/gku1279. Epub 2014 Dec 10. Nucleic Acids Res. 2015. PMID: 25505141 Free PMC article.
EXD2 promotes homologous recombination by facilitating DNA end resection.
Broderick R, Nieminuszczy J, Baddock HT, Deshpande R, Gileadi O, Paull TT, McHugh PJ, Niedzwiedz W. Broderick R, et al. Among authors: gileadi o. Nat Cell Biol. 2016 Mar;18(3):271-280. doi: 10.1038/ncb3303. Epub 2016 Jan 25. Nat Cell Biol. 2016. PMID: 26807646 Free PMC article.
113 results