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Thorough investigation of a canine autoinflammatory disease (AID) confirms one main risk locus and suggests a modifier locus for amyloidosis.
Olsson M, Tintle L, Kierczak M, Perloski M, Tonomura N, Lundquist A, Murén E, Fels M, Tengvall K, Pielberg G, Dufaure de Citres C, Dorso L, Abadie J, Hanson J, Thomas A, Leegwater P, Hedhammar Å, Lindblad-Toh K, Meadows JR. Olsson M, et al. Among authors: perloski m. PLoS One. 2013 Oct 9;8(10):e75242. doi: 10.1371/journal.pone.0075242. eCollection 2013. PLoS One. 2013. PMID: 24130694 Free PMC article.
Novel origins of copy number variation in the dog genome.
Berglund J, Nevalainen EM, Molin AM, Perloski M; LUPA Consortium; André C, Zody MC, Sharpe T, Hitte C, Lindblad-Toh K, Lohi H, Webster MT. Berglund J, et al. Among authors: perloski m. Genome Biol. 2012 Aug 23;13(8):R73. doi: 10.1186/gb-2012-13-8-r73. Genome Biol. 2012. PMID: 22916802 Free PMC article.
Genome-wide association analysis reveals a SOD1 mutation in canine degenerative myelopathy that resembles amyotrophic lateral sclerosis.
Awano T, Johnson GS, Wade CM, Katz ML, Johnson GC, Taylor JF, Perloski M, Biagi T, Baranowska I, Long S, March PA, Olby NJ, Shelton GD, Khan S, O'Brien DP, Lindblad-Toh K, Coates JR. Awano T, et al. Among authors: perloski m. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2794-9. doi: 10.1073/pnas.0812297106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188595 Free PMC article.
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.
Karlsson EK, Sigurdsson S, Ivansson E, Thomas R, Elvers I, Wright J, Howald C, Tonomura N, Perloski M, Swofford R, Biagi T, Fryc S, Anderson N, Courtay-Cahen C, Youell L, Ricketts SL, Mandlebaum S, Rivera P, von Euler H, Kisseberth WC, London CA, Lander ES, Couto G, Comstock K, Starkey MP, Modiano JF, Breen M, Lindblad-Toh K. Karlsson EK, et al. Among authors: perloski m. Genome Biol. 2013 Dec 12;14(12):R132. doi: 10.1186/gb-2013-14-12-r132. Genome Biol. 2013. PMID: 24330828 Free PMC article.
A mutation in hairless dogs implicates FOXI3 in ectodermal development.
Drögemüller C, Karlsson EK, Hytönen MK, Perloski M, Dolf G, Sainio K, Lohi H, Lindblad-Toh K, Leeb T. Drögemüller C, et al. Among authors: perloski m. Science. 2008 Sep 12;321(5895):1462. doi: 10.1126/science.1162525. Science. 2008. PMID: 18787161
A canine chromosome 7 locus confers compulsive disorder susceptibility.
Dodman NH, Karlsson EK, Moon-Fanelli A, Galdzicka M, Perloski M, Shuster L, Lindblad-Toh K, Ginns EI. Dodman NH, et al. Among authors: perloski m. Mol Psychiatry. 2010 Jan;15(1):8-10. doi: 10.1038/mp.2009.111. Mol Psychiatry. 2010. PMID: 20029408 No abstract available.
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