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Mitochondrial complex III is essential for suppressive function of regulatory T cells.
Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS. Weinberg SE, et al. Among authors: sena la. Nature. 2019 Jan;565(7740):495-499. doi: 10.1038/s41586-018-0846-z. Epub 2019 Jan 9. Nature. 2019. PMID: 30626970 Free PMC article.
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J. Peek CB, et al. Among authors: sena la. Science. 2013 Nov 1;342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19. Science. 2013. PMID: 24051248 Free PMC article.
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC.
Sena LA, Kumar R, Sanin DE, Thompson EA, Rosen DM, Dalrymple SL, Antony L, Yang Y, Gomes-Alexandre C, Hicks JL, Jones T, Bowers KA, Eskra JN, Meyers J, Gupta A, Skaist A, Yegnasubramanian S, Luo J, Brennen WN, Kachhap SK, Antonarakis ES, De Marzo AM, Isaacs JT, Markowski MC, Denmeade SR. Sena LA, et al. J Clin Invest. 2022 Dec 1;132(23):e162396. doi: 10.1172/JCI162396. J Clin Invest. 2022. PMID: 36194476 Free PMC article.
There are gremlins in prostate cancer.
Sena LA, Brennen WN, Isaacs JT. Sena LA, et al. Nat Cancer. 2022 May;3(5):530-531. doi: 10.1038/s43018-022-00381-2. Nat Cancer. 2022. PMID: 35624340 Free PMC article.
Bipolar androgen therapy sensitizes castration-resistant prostate cancer to subsequent androgen receptor ablative therapy.
Sena LA, Wang H, Lim ScM SJ, Rifkind I, Ngomba N, Isaacs JT, Luo J, Pratz C, Sinibaldi V, Carducci MA, Paller CJ, Eisenberger MA, Markowski MC, Antonarakis ES, Denmeade SR. Sena LA, et al. Eur J Cancer. 2021 Feb;144:302-309. doi: 10.1016/j.ejca.2020.11.043. Epub 2020 Dec 29. Eur J Cancer. 2021. PMID: 33383350 Free PMC article. Clinical Trial.
42 results