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Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity.
Velez V F, Romano JA, McKown RL, Green K, Zhang L, Raab RW, Ryan DS, Hutnik CM, Frierson HF Jr, Laurie GW. Velez V F, et al. Among authors: mckown rl. Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):2123-32. doi: 10.1167/iovs.12-11488. Invest Ophthalmol Vis Sci. 2013. PMID: 23425695 Free PMC article.
The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease.
Dias-Teixeira K, Horton X, McKown R, Romano J, Laurie GW. Dias-Teixeira K, et al. Adv Exp Med Biol. 2020;1221:747-757. doi: 10.1007/978-3-030-34521-1_31. Adv Exp Med Biol. 2020. PMID: 32274735 Free PMC article. Review.
Focus on molecules: lacritin.
Ma P, Wang N, McKown RL, Raab RW, Laurie GW. Ma P, et al. Among authors: mckown rl. Exp Eye Res. 2008 Mar;86(3):457-8. doi: 10.1016/j.exer.2007.01.025. Epub 2007 Feb 16. Exp Eye Res. 2008. PMID: 17412322 Free PMC article. Review. No abstract available.
Tear lacritin levels by age, sex, and time of day in healthy adults.
Seifert K, Gandia NC, Wilburn JK, Bower KS, Sia RK, Ryan DS, Deaton ML, Still KM, Vassilev VC, Laurie GW, McKown RL. Seifert K, et al. Among authors: mckown rl. Invest Ophthalmol Vis Sci. 2012 Sep 25;53(10):6610-6. doi: 10.1167/iovs.11-8729. Invest Ophthalmol Vis Sci. 2012. PMID: 22918641 Free PMC article.
A cleavage-potentiated fragment of tear lacritin is bactericidal.
McKown RL, Coleman Frazier EV, Zadrozny KK, Deleault AM, Raab RW, Ryan DS, Sia RK, Lee JK, Laurie GW. McKown RL, et al. J Biol Chem. 2014 Aug 8;289(32):22172-82. doi: 10.1074/jbc.M114.570143. Epub 2014 Jun 18. J Biol Chem. 2014. PMID: 24942736 Free PMC article.
30 results