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Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity.
Velez V F, Romano JA, McKown RL, Green K, Zhang L, Raab RW, Ryan DS, Hutnik CM, Frierson HF Jr, Laurie GW. Velez V F, et al. Among authors: ryan ds. Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):2123-32. doi: 10.1167/iovs.12-11488. Invest Ophthalmol Vis Sci. 2013. PMID: 23425695 Free PMC article.
Tear lacritin levels by age, sex, and time of day in healthy adults.
Seifert K, Gandia NC, Wilburn JK, Bower KS, Sia RK, Ryan DS, Deaton ML, Still KM, Vassilev VC, Laurie GW, McKown RL. Seifert K, et al. Among authors: ryan ds. Invest Ophthalmol Vis Sci. 2012 Sep 25;53(10):6610-6. doi: 10.1167/iovs.11-8729. Invest Ophthalmol Vis Sci. 2012. PMID: 22918641 Free PMC article.
A cleavage-potentiated fragment of tear lacritin is bactericidal.
McKown RL, Coleman Frazier EV, Zadrozny KK, Deleault AM, Raab RW, Ryan DS, Sia RK, Lee JK, Laurie GW. McKown RL, et al. Among authors: ryan ds. J Biol Chem. 2014 Aug 8;289(32):22172-82. doi: 10.1074/jbc.M114.570143. Epub 2014 Jun 18. J Biol Chem. 2014. PMID: 24942736 Free PMC article.
Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis.
Georgiev GA, Gh MS, Romano J, Dias Teixeira KL, Struble C, Ryan DS, Sia RK, Kitt JP, Harris JM, Hsu KL, Libby A, Odrich MG, Suárez T, McKown RL, Laurie GW. Georgiev GA, et al. Among authors: ryan ds. J Biol Chem. 2021 Jan-Jun;296:100070. doi: 10.1074/jbc.RA120.015833. Epub 2020 Nov 21. J Biol Chem. 2021. PMID: 33187980 Free PMC article.
Focus on molecules: heparanase.
Zhang Y, Ryan DS, Bower KS, Ilan N, Vlodavsky I, Laurie GW. Zhang Y, et al. Among authors: ryan ds. Exp Eye Res. 2010 Oct;91(4):476-7. doi: 10.1016/j.exer.2010.05.004. Epub 2010 May 15. Exp Eye Res. 2010. PMID: 20478306 Free PMC article. No abstract available.
Anterior segment imaging in combat ocular trauma.
Ryan DS, Sia RK, Colyer M, Stutzman RD, Wroblewski KJ, Mines MJ, Bower KS. Ryan DS, et al. J Ophthalmol. 2013;2013:308259. doi: 10.1155/2013/308259. Epub 2013 Sep 29. J Ophthalmol. 2013. PMID: 24191191 Free PMC article.
81 results