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Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis.
Klingenberg R, Gerdes N, Badeau RM, Gisterå A, Strodthoff D, Ketelhuth DF, Lundberg AM, Rudling M, Nilsson SK, Olivecrona G, Zoller S, Lohmann C, Lüscher TF, Jauhiainen M, Sparwasser T, Hansson GK. Klingenberg R, et al. Among authors: lohmann c. J Clin Invest. 2013 Mar;123(3):1323-34. doi: 10.1172/JCI63891. Epub 2013 Feb 15. J Clin Invest. 2013. PMID: 23426179 Free PMC article.
Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways.
Akhmedov A, Camici GG, Reiner MF, Bonetti NR, Costantino S, Holy EW, Spescha RD, Stivala S, Schaub Clerigué A, Speer T, Breitenstein A, Manz J, Lohmann C, Paneni F, Beer JH, Lüscher TF. Akhmedov A, et al. Among authors: lohmann c. Cardiovasc Res. 2017 Apr 1;113(5):498-507. doi: 10.1093/cvr/cvx015. Cardiovasc Res. 2017. PMID: 28199510
Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo.
Akhmedov A, Rozenberg I, Paneni F, Camici GG, Shi Y, Doerries C, Sledzinska A, Mocharla P, Breitenstein A, Lohmann C, Stein S, von Lukowicz T, Kurrer MO, Borén J, Becher B, Tanner FC, Landmesser U, Matter CM, Lüscher TF. Akhmedov A, et al. Among authors: lohmann c. Eur Heart J. 2014 Oct 21;35(40):2839-48. doi: 10.1093/eurheartj/eht532. Epub 2014 Jan 12. Eur Heart J. 2014. PMID: 24419805 Free article.
Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation.
Winnik S, Lohmann C, Richter EK, Schäfer N, Song WL, Leiber F, Mocharla P, Hofmann J, Klingenberg R, Borén J, Becher B, Fitzgerald GA, Lüscher TF, Matter CM, Beer JH. Winnik S, et al. Among authors: lohmann c. Eur Heart J. 2011 Oct;32(20):2573-84. doi: 10.1093/eurheartj/ehq501. Epub 2011 Jan 31. Eur Heart J. 2011. PMID: 21285075 Free PMC article.
The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression.
Miranda MX, van Tits LJ, Lohmann C, Arsiwala T, Winnik S, Tailleux A, Stein S, Gomes AP, Suri V, Ellis JL, Lutz TA, Hottiger MO, Sinclair DA, Auwerx J, Schoonjans K, Staels B, Lüscher TF, Matter CM. Miranda MX, et al. Among authors: lohmann c. Eur Heart J. 2015 Jan 1;36(1):51-9. doi: 10.1093/eurheartj/ehu095. Epub 2014 Mar 6. Eur Heart J. 2015. PMID: 24603306 Free PMC article.
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis.
Stein S, Lohmann C, Schäfer N, Hofmann J, Rohrer L, Besler C, Rothgiesser KM, Becher B, Hottiger MO, Borén J, McBurney MW, Landmesser U, Lüscher TF, Matter CM. Stein S, et al. Among authors: lohmann c. Eur Heart J. 2010 Sep;31(18):2301-9. doi: 10.1093/eurheartj/ehq107. Epub 2010 Apr 23. Eur Heart J. 2010. PMID: 20418343 Free PMC article.
Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development.
Winnik S, Gaul DS, Preitner F, Lohmann C, Weber J, Miranda MX, Liu Y, van Tits LJ, Mateos JM, Brokopp CE, Auwerx J, Thorens B, Lüscher TF, Matter CM. Winnik S, et al. Among authors: lohmann c. Basic Res Cardiol. 2014 Jan;109(1):399. doi: 10.1007/s00395-013-0399-0. Epub 2013 Dec 27. Basic Res Cardiol. 2014. PMID: 24370889 Free PMC article.
533 results