Kulkarni P - Search Results

1

Novel N-indolylmethyl substituted olanzapine derivatives: their design, synthesis and evaluation as PDE4B inhibitors.

Gorja DR, Mukherjee S, Meda CL, Deora GS, Kumar KL, Jain A, Chaudhari GH, Chennubhotla KS, Banote RK, Kulkarni P, Parsa KV, Mukkanti K, Pal M. Gorja DR, et al. Among authors: kulkarni p. Org Biomol Chem. 2013 Apr 7;11(13):2075-9. doi: 10.1039/c3ob27424a. Org Biomol Chem. 2013. PMID: 23436140

2

Transition metal free hydrolysis/cyclization strategy in a single pot: synthesis of fused furo N-heterocycles of pharmacological interest.

Nakhi A, Rahman MS, Seerapu GP, Banote RK, Kumar KL, Kulkarni P, Haldar D, Pal M. Nakhi A, et al. Among authors: kulkarni p. Org Biomol Chem. 2013 Aug 14;11(30):4930-4. doi: 10.1039/c3ob41069b. Epub 2013 Jul 3. Org Biomol Chem. 2013. PMID: 23824158

3

Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo.

Babu PV, Mukherjee S, Deora GS, Chennubhotla KS, Medisetti R, Yellanki S, Kulkarni P, Sripelly S, Parsa KV, Chatti K, Mukkanti K, Pal M. Babu PV, et al. Among authors: kulkarni p. Org Biomol Chem. 2013 Oct 21;11(39):6680-5. doi: 10.1039/c3ob41504j. Epub 2013 Aug 29. Org Biomol Chem. 2013. PMID: 23986357

4

InCl₃ mediated heteroarylation of indoles and their derivatization via CH activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis.

Sunke R, Bankala R, Thirupataiah B, Ramarao EVVS, Kumar JS, Doss HM, Medishetti R, Kulkarni P, Kapavarapu RK, Rasool M, Mudgal J, Mathew JE, Shenoy GG, Parsa KVL, Pal M. Sunke R, et al. Among authors: kulkarni p. Eur J Med Chem. 2019 Jul 15;174:198-215. doi: 10.1016/j.ejmech.2019.04.020. Epub 2019 Apr 16. Eur J Med Chem. 2019. PMID: 31035240

5

Optimization of the adult zebrafish ECG method for assessment of drug-induced QTc prolongation.

Chaudhari GH, Chennubhotla KS, Chatti K, Kulkarni P. Chaudhari GH, et al. Among authors: kulkarni p. J Pharmacol Toxicol Methods. 2013 Mar-Apr;67(2):115-20. doi: 10.1016/j.vascn.2013.01.007. Epub 2013 Jan 24. J Pharmacol Toxicol Methods. 2013. PMID: 23353637

6

AlCl3-mediated hydroarylation-heteroarylation in a single pot: a direct access to densely functionalized olefins of pharmacological interest.

Nakhi A, Archana S, Seerapu GP, Chennubhotla KS, Kumar KL, Kulkarni P, Haldar D, Pal M. Nakhi A, et al. Among authors: kulkarni p. Chem Commun (Camb). 2013 Jul 18;49(56):6268-70. doi: 10.1039/c3cc42840k. Chem Commun (Camb). 2013. PMID: 23732749

7

Isovanillin derived N-(un)substituted hydroxylamines possessing an ortho-allylic group: valuable precursors to bioactive N-heterocycles.

Dulla B, Tangellamudi ND, Balasubramanian S, Yellanki S, Medishetti R, Kumar Banote R, Hari Chaudhari G, Kulkarni P, Iqbal J, Reiser O, Pal M. Dulla B, et al. Among authors: kulkarni p. Org Biomol Chem. 2014 Apr 28;12(16):2552-8. doi: 10.1039/c3ob42460j. Org Biomol Chem. 2014. PMID: 24576957

8

A Pd-based regioselective strategy to indole-1,2-fused 8- and 9-membered rings: their evaluation as potential scaffolds for apoptosis in zebrafish.

Prasad B, Sreenivas BY, Sushma A, Yellanki S, Medisetti R, Kulkarni P, Pal M. Prasad B, et al. Among authors: kulkarni p. Org Biomol Chem. 2014 May 14;12(18):2864-8. doi: 10.1039/c4ob00140k. Org Biomol Chem. 2014. PMID: 24676598

9

Ligand-free MCR for linking quinoxaline framework with a benzimidazole nucleus: a new strategy for the identification of novel hybrid molecules as potential inducers of apoptosis.

Sunke R, Babu PV, Yellanki S, Medishetti R, Kulkarni P, Pal M. Sunke R, et al. Among authors: kulkarni p. Org Biomol Chem. 2014 Sep 21;12(35):6800-5. doi: 10.1039/c4ob01268b. Org Biomol Chem. 2014. PMID: 25066016

10

Ligand-free Pd-catalyzed C-N cross-coupling/cyclization strategy: an unprecedented access to 1-thienyl pyrroloquinoxalines for the new approach towards apoptosis.

Kolli SK, Nakhi A, Archana S, Saridena M, Deora GS, Yellanki S, Medisetti R, Kulkarni P, Ramesh Raju R, Pal M. Kolli SK, et al. Among authors: kulkarni p. Eur J Med Chem. 2014 Oct 30;86:270-8. doi: 10.1016/j.ejmech.2014.08.057. Epub 2014 Aug 17. Eur J Med Chem. 2014. PMID: 25171781

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