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Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy.
van de Weijer T, Havekes B, Bilet L, Hoeks J, Sparks L, Bosma M, Paglialunga S, Jorgensen J, Janssen MC, Schaart G, Sauerwein H, Smeets JL, Wildberger J, Zechner R, Schrauwen-Hinderling VB, Hesselink MK, Schrauwen P. van de Weijer T, et al. Among authors: zechner r. Circ Res. 2013 Mar 1;112(5):e51-4. doi: 10.1161/CIRCRESAHA.113.300944. Circ Res. 2013. PMID: 23449549 No abstract available.
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R. Haemmerle G, et al. Among authors: zechner r. Nat Med. 2011 Aug 21;17(9):1076-85. doi: 10.1038/nm.2439. Nat Med. 2011. PMID: 21857651 Free PMC article.
Cardiac oxidative stress in a mouse model of neutral lipid storage disease.
Schrammel A, Mussbacher M, Winkler S, Haemmerle G, Stessel H, Wölkart G, Zechner R, Mayer B. Schrammel A, et al. Among authors: zechner r. Biochim Biophys Acta. 2013 Nov;1831(11):1600-8. doi: 10.1016/j.bbalip.2013.07.004. Epub 2013 Jul 15. Biochim Biophys Acta. 2013. PMID: 23867907 Free PMC article.
Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction.
Kienesberger PC, Pulinilkunnil T, Sung MM, Nagendran J, Haemmerle G, Kershaw EE, Young ME, Light PE, Oudit GY, Zechner R, Dyck JR. Kienesberger PC, et al. Among authors: zechner r. Mol Cell Biol. 2012 Feb;32(4):740-50. doi: 10.1128/MCB.06470-11. Epub 2011 Dec 12. Mol Cell Biol. 2012. PMID: 22158969 Free PMC article.
Cell biology: Another way to get rid of fat.
Zechner R, Madeo F. Zechner R, et al. Nature. 2009 Apr 30;458(7242):1118-9. doi: 10.1038/4581118a. Nature. 2009. PMID: 19407787 No abstract available.
244 results