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Mycobacterium tuberculosis-specific CD8+ T cells are functionally and phenotypically different between latent infection and active disease.
Rozot V, Vigano S, Mazza-Stalder J, Idrizi E, Day CL, Perreau M, Lazor-Blanchet C, Petruccioli E, Hanekom W, Goletti D, Bart PA, Nicod L, Pantaleo G, Harari A. Rozot V, et al. Among authors: goletti d. Eur J Immunol. 2013 Jun;43(6):1568-77. doi: 10.1002/eji.201243262. Eur J Immunol. 2013. PMID: 23456989 Free PMC article.
Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood.
Chiacchio T, Petruccioli E, Vanini V, Butera O, Cuzzi G, Petrone L, Matteucci G, Lauria FN, Franken KL, Girardi E, Ottenhoff TH, Goletti D. Chiacchio T, et al. Among authors: goletti d. PLoS One. 2011;6(11):e27539. doi: 10.1371/journal.pone.0027539. Epub 2011 Nov 10. PLoS One. 2011. PMID: 22102905 Free PMC article.
Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis.
Rozot V, Patrizia A, Vigano S, Mazza-Stalder J, Idrizi E, Day CL, Perreau M, Lazor-Blanchet C, Ohmiti K, Goletti D, Bart PA, Hanekom W, Scriba TJ, Nicod L, Pantaleo G, Harari A. Rozot V, et al. Among authors: goletti d. Clin Infect Dis. 2015 Feb 1;60(3):432-7. doi: 10.1093/cid/ciu795. Epub 2014 Oct 31. Clin Infect Dis. 2015. PMID: 25362202 Free PMC article.
337 results