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490 results

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Page 1
Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Himes BE, et al. Among authors: szefler sj. PLoS One. 2013;8(2):e56179. doi: 10.1371/journal.pone.0056179. Epub 2013 Feb 14. PLoS One. 2013. PMID: 23457522 Free PMC article.
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF Jr, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST. Tantisira KG, et al. N Engl J Med. 2011 Sep 29;365(13):1173-83. doi: 10.1056/NEJMoa0911353. Epub 2011 Sep 26. N Engl J Med. 2011. PMID: 21991891 Free PMC article.
Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.
Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E; SHARP Investigators. Tantisira KG, et al. Among authors: szefler sj. Am J Respir Crit Care Med. 2012 Jun 15;185(12):1286-91. doi: 10.1164/rccm.201111-2061OC. Epub 2012 Apr 26. Am J Respir Crit Care Med. 2012. PMID: 22538805 Free PMC article. Clinical Trial.
Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA Jr, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST. Himes BE, et al. Among authors: szefler sj. PLoS Genet. 2012 Jul;8(7):e1002824. doi: 10.1371/journal.pgen.1002824. Epub 2012 Jul 5. PLoS Genet. 2012. PMID: 22792082 Free PMC article.
ITGB5 and AGFG1 variants are associated with severity of airway responsiveness.
Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. Himes BE, et al. Among authors: szefler sj. BMC Med Genet. 2013 Aug 28;14:86. doi: 10.1186/1471-2350-14-86. BMC Med Genet. 2013. PMID: 23984888 Free PMC article.
A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes.
Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Avila L, Soto-Quiros M, Barraza-Villareal A, Lemanske RF Jr, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Celedón JC, Carey VJ, Weiss ST, Raby BA. Sharma S, et al. Among authors: szefler sj. J Allergy Clin Immunol. 2014 Nov;134(5):1153-62. doi: 10.1016/j.jaci.2014.04.011. Epub 2014 Jun 13. J Allergy Clin Immunol. 2014. PMID: 24934276 Free PMC article. Clinical Trial.
Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.
Murphy A, Chu JH, Xu M, Carey VJ, Lazarus R, Liu A, Szefler SJ, Strunk R, Demuth K, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF Jr, Klanderman BJ, Senter-Sylvia J, Ziniti J, Lange C, Pastinen T, Raby BA. Murphy A, et al. Among authors: szefler sj. Hum Mol Genet. 2010 Dec 1;19(23):4745-57. doi: 10.1093/hmg/ddq392. Epub 2010 Sep 10. Hum Mol Genet. 2010. PMID: 20833654 Free PMC article.
490 results