Huang DC - Search Results

1

MCMV-mediated inhibition of the pro-apoptotic Bak protein is required for optimal in vivo replication.

Fleming P, Kvansakul M, Voigt V, Kile BT, Kluck RM, Huang DC, Degli-Esposti MA, Andoniou CE. Fleming P, et al. Among authors: huang dc. PLoS Pathog. 2013 Feb;9(2):e1003192. doi: 10.1371/journal.ppat.1003192. Epub 2013 Feb 28. PLoS Pathog. 2013. PMID: 23468630 Free PMC article.

2

Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis.

Fischer SF, Ludwig H, Holzapfel J, Kvansakul M, Chen L, Huang DC, Sutter G, Knese M, Häcker G. Fischer SF, et al. Among authors: huang dc. Cell Death Differ. 2006 Jan;13(1):109-18. doi: 10.1038/sj.cdd.4401718. Cell Death Differ. 2006. PMID: 16003387

3

CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13.

Fairlie WD, Perugini MA, Kvansakul M, Chen L, Huang DC, Colman PM. Fairlie WD, et al. Among authors: huang dc. Cell Death Differ. 2006 Mar;13(3):426-34. doi: 10.1038/sj.cdd.4401762. Cell Death Differ. 2006. PMID: 16167070

4

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.

Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC. Willis SN, et al. Among authors: huang dc. Science. 2007 Feb 9;315(5813):856-9. doi: 10.1126/science.1133289. Science. 2007. PMID: 17289999

5

Programmed anuclear cell death delimits platelet life span.

Mason KD, Carpinelli MR, Fletcher JI, Collinge JE, Hilton AA, Ellis S, Kelly PN, Ekert PG, Metcalf D, Roberts AW, Huang DC, Kile BT. Mason KD, et al. Among authors: huang dc. Cell. 2007 Mar 23;128(6):1173-86. doi: 10.1016/j.cell.2007.01.037. Cell. 2007. PMID: 17382885 Free article.

6

A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.

Kvansakul M, van Delft MF, Lee EF, Gulbis JM, Fairlie WD, Huang DC, Colman PM. Kvansakul M, et al. Among authors: huang dc. Mol Cell. 2007 Mar 23;25(6):933-42. doi: 10.1016/j.molcel.2007.02.004. Mol Cell. 2007. PMID: 17386268 Free article.

7

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.

Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM. Uren RT, et al. Among authors: huang dc. J Cell Biol. 2007 Apr 23;177(2):277-87. doi: 10.1083/jcb.200606065. J Cell Biol. 2007. PMID: 17452531 Free PMC article.

8

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

Huntington ND, Puthalakath H, Gunn P, Naik E, Michalak EM, Smyth MJ, Tabarias H, Degli-Esposti MA, Dewson G, Willis SN, Motoyama N, Huang DC, Nutt SL, Tarlinton DM, Strasser A. Huntington ND, et al. Among authors: huang dc. Nat Immunol. 2007 Aug;8(8):856-63. doi: 10.1038/ni1487. Epub 2007 Jul 8. Nat Immunol. 2007. PMID: 17618288 Free PMC article.

9

Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands.

Kvansakul M, Yang H, Fairlie WD, Czabotar PE, Fischer SF, Perugini MA, Huang DC, Colman PM. Kvansakul M, et al. Among authors: huang dc. Cell Death Differ. 2008 Oct;15(10):1564-71. doi: 10.1038/cdd.2008.83. Epub 2008 Jun 13. Cell Death Differ. 2008. PMID: 18551131

10

Virally mediated inhibition of Bax in leukocytes promotes dissemination of murine cytomegalovirus.

Manzur M, Fleming P, Huang DC, Degli-Esposti MA, Andoniou CE. Manzur M, et al. Among authors: huang dc. Cell Death Differ. 2009 Feb;16(2):312-20. doi: 10.1038/cdd.2008.152. Epub 2008 Oct 24. Cell Death Differ. 2009. PMID: 18949000

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