Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.
Kiezun A, Pulit SL, Francioli LC, van Dijk F, Swertz M, Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C; Genome of the Netherlands Consortium; de Bakker PI, Sunyaev SR.
Kiezun A, et al. Among authors: sunyaev sr.
PLoS Genet. 2013;9(2):e1003301. doi: 10.1371/journal.pgen.1003301. Epub 2013 Feb 28.
PLoS Genet. 2013.
PMID: 23468643
Free PMC article.