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Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.
Kiezun A, Pulit SL, Francioli LC, van Dijk F, Swertz M, Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C; Genome of the Netherlands Consortium; de Bakker PI, Sunyaev SR. Kiezun A, et al. Among authors: van duijn cm, van dijk f, van ommen gj. PLoS Genet. 2013;9(2):e1003301. doi: 10.1371/journal.pgen.1003301. Epub 2013 Feb 28. PLoS Genet. 2013. PMID: 23468643 Free PMC article.
Role of APOE in dementia: A critical reappraisal.
de Knijff P, van Duijn CM. de Knijff P, et al. Among authors: van duijn cm. Haemostasis. 1998 May-Aug;28(3-4):195-201. doi: 10.1159/000022430. Haemostasis. 1998. PMID: 10420066 Review.
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