Der BS - Search Results

1

Combined computational design of a zinc-binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin binding.

Der BS, Jha RK, Lewis SM, Thompson PM, Guntas G, Kuhlman B. Der BS, et al. Proteins. 2013 Jul;81(7):1245-55. doi: 10.1002/prot.24280. Epub 2013 Apr 20. Proteins. 2013. PMID: 23504819 Free PMC article.

2

Strategies to control the binding mode of de novo designed protein interactions.

Der BS, Kuhlman B. Der BS, et al. Curr Opin Struct Biol. 2013 Aug;23(4):639-46. doi: 10.1016/j.sbi.2013.04.010. Epub 2013 May 31. Curr Opin Struct Biol. 2013. PMID: 23731800 Free PMC article. Review.

3

Probing the minimal determinants of zinc binding with computational protein design.

Guffy SL, Der BS, Kuhlman B. Guffy SL, et al. Among authors: der bs. Protein Eng Des Sel. 2016 Aug;29(8):327-338. doi: 10.1093/protein/gzw026. Epub 2016 Jun 29. Protein Eng Des Sel. 2016. PMID: 27358168 Free PMC article.

4

Biochemistry. From computational design to a protein that binds.

Der BS, Kuhlman B. Der BS, et al. Science. 2011 May 13;332(6031):801-2. doi: 10.1126/science.1207082. Science. 2011. PMID: 21566181 No abstract available.

5

Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer.

Der BS, Machius M, Miley MJ, Mills JL, Szyperski T, Kuhlman B. Der BS, et al. J Am Chem Soc. 2012 Jan 11;134(1):375-85. doi: 10.1021/ja208015j. Epub 2011 Dec 15. J Am Chem Soc. 2012. PMID: 22092237 Free PMC article.

6

Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering.

Der BS, Edwards DR, Kuhlman B. Der BS, et al. Biochemistry. 2012 May 8;51(18):3933-40. doi: 10.1021/bi201881p. Epub 2012 Apr 24. Biochemistry. 2012. PMID: 22510088 Free PMC article.

7

Cages from coils.

Der BS, Kuhlman B. Der BS, et al. Nat Biotechnol. 2013 Sep;31(9):809-10. doi: 10.1038/nbt.2670. Nat Biotechnol. 2013. PMID: 24022157 No abstract available.

8

Computational de novo design of a four-helix bundle protein--DND_4HB.

Murphy GS, Sathyamoorthy B, Der BS, Machius MC, Pulavarti SV, Szyperski T, Kuhlman B. Murphy GS, et al. Among authors: der bs. Protein Sci. 2015 Apr;24(4):434-45. doi: 10.1002/pro.2577. Epub 2014 Nov 6. Protein Sci. 2015. PMID: 25287625 Free PMC article.

9

Alternative computational protocols for supercharging protein surfaces for reversible unfolding and retention of stability.

Der BS, Kluwe C, Miklos AE, Jacak R, Lyskov S, Gray JJ, Georgiou G, Ellington AD, Kuhlman B. Der BS, et al. PLoS One. 2013 May 31;8(5):e64363. doi: 10.1371/journal.pone.0064363. Print 2013. PLoS One. 2013. PMID: 23741319 Free PMC article.

10

Evolution of a highly active and enantiospecific metalloenzyme from short peptides.

Studer S, Hansen DA, Pianowski ZL, Mittl PRE, Debon A, Guffy SL, Der BS, Kuhlman B, Hilvert D. Studer S, et al. Among authors: der bs. Science. 2018 Dec 14;362(6420):1285-1288. doi: 10.1126/science.aau3744. Science. 2018. PMID: 30545884

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