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Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations.
Ramalho-Carvalho J, Pires M, Lisboa S, Graça I, Rocha P, Barros-Silva JD, Savva-Bordalo J, Maurício J, Resende M, Teixeira MR, Honavar M, Henrique R, Jerónimo C. Ramalho-Carvalho J, et al. Among authors: mauricio j. PLoS One. 2013;8(3):e58206. doi: 10.1371/journal.pone.0058206. Epub 2013 Mar 11. PLoS One. 2013. PMID: 23505468 Free PMC article.
Differential methylation EPIC analysis discloses cisplatin-resistance related hypermethylation and tumor-specific heterogeneity within matched primary and metastatic testicular germ cell tumor patient tissue samples.
Lobo J, Constâncio V, Leite-Silva P, Guimarães R, Cantante M, Braga I, Maurício J, Looijenga LHJ, Henrique R, Jerónimo C. Lobo J, et al. Among authors: mauricio j. Clin Epigenetics. 2021 Apr 6;13(1):70. doi: 10.1186/s13148-021-01048-y. Clin Epigenetics. 2021. PMID: 33823933 Free PMC article.
Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors.
Lobo J, Constâncio V, Guimarães-Teixeira C, Leite-Silva P, Miranda-Gonçalves V, Sequeira JP, Pistoni L, Guimarães R, Cantante M, Braga I, Maurício J, Looijenga LHJ, Henrique R, Jerónimo C. Lobo J, et al. Among authors: mauricio j. Mol Oncol. 2021 Apr;15(4):846-865. doi: 10.1002/1878-0261.12909. Epub 2021 Mar 2. Mol Oncol. 2021. PMID: 33513287 Free PMC article.
Detailed Characterization of Immune Cell Infiltrate and Expression of Immune Checkpoint Molecules PD-L1/CTLA-4 and MMR Proteins in Testicular Germ Cell Tumors Disclose Novel Disease Biomarkers.
Lobo J, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Maurício J, Oliveira J, Jerónimo C, Henrique R. Lobo J, et al. Among authors: mauricio j. Cancers (Basel). 2019 Oct 11;11(10):1535. doi: 10.3390/cancers11101535. Cancers (Basel). 2019. PMID: 31614500 Free PMC article.
The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors.
Miranda-Gonçalves V, Lobo J, Guimarães-Teixeira C, Barros-Silva D, Guimarães R, Cantante M, Braga I, Maurício J, Oing C, Honecker F, Nettersheim D, Looijenga LHJ, Henrique R, Jerónimo C. Miranda-Gonçalves V, et al. Among authors: mauricio j. J Exp Clin Cancer Res. 2021 Aug 25;40(1):268. doi: 10.1186/s13046-021-02072-9. J Exp Clin Cancer Res. 2021. PMID: 34446080 Free PMC article.
Ki67 and LSD1 Expression in Testicular Germ Cell Tumors Is Not Associated with Patient Outcome: Investigation Using a Digital Pathology Algorithm.
Lourenço BC, Guimarães-Teixeira C, Flores BCT, Miranda-Gonçalves V, Guimarães R, Cantante M, Lopes P, Braga I, Maurício J, Jerónimo C, Henrique R, Lobo J. Lourenço BC, et al. Among authors: mauricio j. Life (Basel). 2022 Feb 10;12(2):264. doi: 10.3390/life12020264. Life (Basel). 2022. PMID: 35207551 Free PMC article.
DigiMir Test: Establishing a Novel Pipeline for MiR-371a Quantification Using Droplet Digital PCR in Liquid Biopsies From Testicular Germ Cell Tumor Patients.
Sequeira JP, Lobo J, Constâncio V, Brito-Rocha T, Carvalho-Maia C, Braga I, Maurício J, Henrique R, Jerónimo C. Sequeira JP, et al. Among authors: mauricio j. Front Oncol. 2022 Jun 10;12:876732. doi: 10.3389/fonc.2022.876732. eCollection 2022. Front Oncol. 2022. PMID: 35756620 Free PMC article.
180 results