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Page 1
Genome-wide association study of body mass index in 23 000 individuals with and without asthma.
Melén E, Granell R, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D, Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch NM, Curjuric I, Imboden M, Rochat T, Henderson J, Sterne JA, McArdle WL, Hui J, James AL, William Musk A, Palmer LJ, Becker A, Kozyrskyj AL, Chan-Young M, Park JE, Leung A, Daley D, Freidin MB, Deev IA, Ogorodova LM, Puzyrev VP, Celedón JC, Brehm JM, Cloutier MM, Canino G, Acosta-Pérez E, Soto-Quiros M, Avila L, Bergström A, Magnusson J, Söderhäll C, Kull I, Scholtens S, Marike Boezen H, Koppelman GH, Wijga AH, Marenholz I, Esparza-Gordillo J, Lau S, Lee YA, Standl M, Tiesler CM, Flexeder C, Heinrich J, Myers RA, Ober C, Nicolae DL, Farrall M, Kumar A, Moffatt MF, Cookson WO, Lasky-Su J. Melén E, et al. Clin Exp Allergy. 2013 Apr;43(4):463-74. doi: 10.1111/cea.12054. Clin Exp Allergy. 2013. PMID: 23517042 Free PMC article.
Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.
Scholtens S, Postma DS, Moffatt MF, Panasevich S, Granell R, Henderson AJ, Melén E, Nyberg F, Pershagen G, Jarvis D, Ramasamy A, Wjst M, Svanes C, Bouzigon E, Demenais F, Kauffmann F, Siroux V, von Mutius E, Ege MJ, Braun-Fahrländer C, Genuneit J; GABRIELA study group; Brunekreef B, Smit HA, Wijga AH, Kerkhof M, Curjuric I, Imboden M, Thun GA, Probst-Hensch N, Freidin MB, Bragina EIu, Deev IA, Puzyrev VP, Daley D, Park J, Becker A, Chan-Yeung M, Kozyrskyj AL, Pare P, Marenholz I, Lau S, Keil T, Lee YA, Kabesch M, Wijmenga C, Franke L, Nolte IM, Vonk J, Kumar A, Farrall M, Cookson WO, Strachan DP, Koppelman GH, Boezen HM. Scholtens S, et al. J Allergy Clin Immunol. 2014 Mar;133(3):885-8. doi: 10.1016/j.jaci.2013.08.049. Epub 2013 Dec 6. J Allergy Clin Immunol. 2014. PMID: 24315450 Free PMC article. No abstract available.
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, Ang WQ, McArdle W, Arnold A, Homuth G, Demenais F, Bouzigon E, Söderhäll C, Pershagen G, de Jongste JC, Postma DS, Braun-Fahrländer C, Horak E, Ogorodova LM, Puzyrev VP, Bragina EY, Hudson TJ, Morin C, Duffy DL, Marks GB, Robertson CF, Montgomery GW, Musk B, Thompson PJ, Martin NG, James A, Sleiman P, Toskala E, Rodriguez E, Fölster-Holst R, Franke A, Lieb W, Gieger C, Heinzmann A, Rietschel E, Keil T, Cichon S, Nöthen MM, Pennell CE, Sly PD, Schmidt CO, Matanovic A, Schneider V, Heinig M, Hübner N, Holt PG, Lau S, Kabesch M, Weidinger S, Hakonarson H, Ferreira MAR, Laprise C, Freidin MB, Genuneit J, Koppelman GH, Melén E, Dizier MH, Henderson AJ, Lee YA. Marenholz I, et al. Nat Commun. 2015 Nov 6;6:8804. doi: 10.1038/ncomms9804. Nat Commun. 2015. PMID: 26542096 Free PMC article.
A large-scale, consortium-based genomewide association study of asthma.
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM; GABRIEL Consortium. Moffatt MF, et al. N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312. N Engl J Med. 2010. PMID: 20860503 Free PMC article.
Asthma in farm children is more determined by genetic polymorphisms and in non-farm children by environmental factors.
Krautenbacher N, Kabesch M, Horak E, Braun-Fahrländer C, Genuneit J, Boznanski A, von Mutius E, Theis F, Fuchs C, Ege MJ; GABRIELA, PASTURE study groups. Krautenbacher N, et al. Among authors: braun fahrlander c. Pediatr Allergy Immunol. 2021 Feb;32(2):295-304. doi: 10.1111/pai.13385. Epub 2020 Oct 15. Pediatr Allergy Immunol. 2021. PMID: 32997854
Gene-environment interaction for childhood asthma and exposure to farming in Central Europe.
Ege MJ, Strachan DP, Cookson WO, Moffatt MF, Gut I, Lathrop M, Kabesch M, Genuneit J, Büchele G, Sozanska B, Boznanski A, Cullinan P, Horak E, Bieli C, Braun-Fahrländer C, Heederik D, von Mutius E; GABRIELA Study Group. Ege MJ, et al. J Allergy Clin Immunol. 2011 Jan;127(1):138-44, 144.e1-4. doi: 10.1016/j.jaci.2010.09.041. J Allergy Clin Immunol. 2011. PMID: 21211648
Bacterial microbiota of the upper respiratory tract and childhood asthma.
Depner M, Ege MJ, Cox MJ, Dwyer S, Walker AW, Birzele LT, Genuneit J, Horak E, Braun-Fahrländer C, Danielewicz H, Maier RM, Moffatt MF, Cookson WO, Heederik D, von Mutius E, Legatzki A. Depner M, et al. J Allergy Clin Immunol. 2017 Mar;139(3):826-834.e13. doi: 10.1016/j.jaci.2016.05.050. Epub 2016 Jul 27. J Allergy Clin Immunol. 2017. PMID: 27576124
Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma.
Acevedo N, Sääf A, Söderhäll C, Melén E, Mandelin J, Pietras CO, Ezer S, Karisola P, Vendelin J, Gennäs GB, Yli-Kauhaluoma J, Alenius H, von Mutius E, Doekes G, Braun-Fahrländer C, Riedler J, van Hage M, D'Amato M, Scheynius A, Pershagen G, Kere J, Pulkkinen V. Acevedo N, et al. PLoS One. 2013;8(4):e60111. doi: 10.1371/journal.pone.0060111. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565190 Free PMC article.
Rule-based models of the interplay between genetic and environmental factors in childhood allergy.
Bornelöv S, Sääf A, Melén E, Bergström A, Torabi Moghadam B, Pulkkinen V, Acevedo N, Orsmark Pietras C, Ege M, Braun-Fahrländer C, Riedler J, Doekes G, Kabesch M, van Hage M, Kere J, Scheynius A, Söderhäll C, Pershagen G, Komorowski J. Bornelöv S, et al. PLoS One. 2013 Nov 19;8(11):e80080. doi: 10.1371/journal.pone.0080080. eCollection 2013. PLoS One. 2013. PMID: 24260339 Free PMC article.
195 results