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Page 1
Genome-wide association study of body mass index in 23 000 individuals with and without asthma.
Melén E, Granell R, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D, Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, Kauffmann F, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch NM, Curjuric I, Imboden M, Rochat T, Henderson J, Sterne JA, McArdle WL, Hui J, James AL, William Musk A, Palmer LJ, Becker A, Kozyrskyj AL, Chan-Young M, Park JE, Leung A, Daley D, Freidin MB, Deev IA, Ogorodova LM, Puzyrev VP, Celedón JC, Brehm JM, Cloutier MM, Canino G, Acosta-Pérez E, Soto-Quiros M, Avila L, Bergström A, Magnusson J, Söderhäll C, Kull I, Scholtens S, Marike Boezen H, Koppelman GH, Wijga AH, Marenholz I, Esparza-Gordillo J, Lau S, Lee YA, Standl M, Tiesler CM, Flexeder C, Heinrich J, Myers RA, Ober C, Nicolae DL, Farrall M, Kumar A, Moffatt MF, Cookson WO, Lasky-Su J. Melén E, et al. Among authors: heinzmann a. Clin Exp Allergy. 2013 Apr;43(4):463-74. doi: 10.1111/cea.12054. Clin Exp Allergy. 2013. PMID: 23517042 Free PMC article.
Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.
Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M. Schieck M, et al. Among authors: heinzmann a. J Allergy Clin Immunol. 2016 Aug;138(2):421-31. doi: 10.1016/j.jaci.2015.12.1305. Epub 2016 Feb 20. J Allergy Clin Immunol. 2016. PMID: 26906082
Meta-analysis identifies seven susceptibility loci involved in the atopic march.
Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, Ang WQ, McArdle W, Arnold A, Homuth G, Demenais F, Bouzigon E, Söderhäll C, Pershagen G, de Jongste JC, Postma DS, Braun-Fahrländer C, Horak E, Ogorodova LM, Puzyrev VP, Bragina EY, Hudson TJ, Morin C, Duffy DL, Marks GB, Robertson CF, Montgomery GW, Musk B, Thompson PJ, Martin NG, James A, Sleiman P, Toskala E, Rodriguez E, Fölster-Holst R, Franke A, Lieb W, Gieger C, Heinzmann A, Rietschel E, Keil T, Cichon S, Nöthen MM, Pennell CE, Sly PD, Schmidt CO, Matanovic A, Schneider V, Heinig M, Hübner N, Holt PG, Lau S, Kabesch M, Weidinger S, Hakonarson H, Ferreira MAR, Laprise C, Freidin MB, Genuneit J, Koppelman GH, Melén E, Dizier MH, Henderson AJ, Lee YA. Marenholz I, et al. Among authors: heinzmann a. Nat Commun. 2015 Nov 6;6:8804. doi: 10.1038/ncomms9804. Nat Commun. 2015. PMID: 26542096 Free PMC article.
Polymorphisms in the IRF-4 gene, asthma and recurrent bronchitis in children.
Pinto LA, Michel S, Klopp N, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Gorski M, Illig T, Kabesch M. Pinto LA, et al. Among authors: heinzmann a. Clin Exp Allergy. 2013 Oct;43(10):1152-9. doi: 10.1111/cea.12175. Clin Exp Allergy. 2013. PMID: 24074333
Nocturnal asthma is affected by genetic interactions between RORA and NPSR1.
Gaertner VD, Michel S, Curtin JA, Pulkkinen V, Acevedo N, Söderhäll C, von Berg A, Bufe A, Laub O, Rietschel E, Heinzmann A, Simma B, Vogelberg C, Pershagen G, Melén E, Simpson A, Custovic A, Kere J, Kabesch M. Gaertner VD, et al. Among authors: heinzmann a. Pediatr Pulmonol. 2019 Jun;54(6):847-857. doi: 10.1002/ppul.24292. Epub 2019 Mar 29. Pediatr Pulmonol. 2019. PMID: 30927345
A role of FCER1A and FCER2 polymorphisms in IgE regulation.
Sharma V, Michel S, Gaertner V, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Potaczek DP, Kabesch M. Sharma V, et al. Among authors: heinzmann a. Allergy. 2014 Feb;69(2):231-6. doi: 10.1111/all.12336. Epub 2013 Dec 20. Allergy. 2014. PMID: 24354852
Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project data.
Sharma V, Michel S, Gaertner V, Franke A, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Zeilinger S, Illig T, Schedel M, Potaczek DP, Kabesch M. Sharma V, et al. Among authors: heinzmann a. Allergy. 2014 Aug;69(8):1077-84. doi: 10.1111/all.12431. Epub 2014 Jun 14. Allergy. 2014. PMID: 24930997
Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.
Toncheva AA, Potaczek DP, Schedel M, Gersting SW, Michel S, Krajnov N, Gaertner VD, Klingbeil JM, Illig T, Franke A, Winkler C, Hohlfeld JM, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Muntau AC, Kabesch M. Toncheva AA, et al. Among authors: heinzmann a. Allergy. 2015 Oct;70(10):1288-99. doi: 10.1111/all.12652. Epub 2015 Jul 20. Allergy. 2015. PMID: 26011647
Genetic variation in the Toll-like receptor signaling pathway is associated with childhood asthma.
Pandey RC, Michel S, Tesse R, Binia A, Schedel M, Liang L, Klopp N, Franke A, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Illig T, Kabesch M. Pandey RC, et al. Among authors: heinzmann a. J Allergy Clin Immunol. 2013 Feb;131(2):602-5. doi: 10.1016/j.jaci.2012.10.061. Epub 2012 Dec 28. J Allergy Clin Immunol. 2013. PMID: 23273951 No abstract available.
Polymorphisms in extracellular signal-regulated kinase family influence genetic susceptibility to asthma.
Pandey RC, Michel S, Schieck M, Binia A, Liang L, Klopp N, Franke A, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Illig T, Kabesch M. Pandey RC, et al. Among authors: heinzmann a. J Allergy Clin Immunol. 2013 Apr;131(4):1245-7. doi: 10.1016/j.jaci.2012.12.675. Epub 2013 Feb 4. J Allergy Clin Immunol. 2013. PMID: 23384682 No abstract available.
180 results