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Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.
Castells X, Karanović S, Ardin M, Tomić K, Xylinas E, Durand G, Villar S, Forey N, Le Calvez-Kelm F, Voegele C, Karlović K, Mišić M, Dittrich D, Dolgalev I, McKay J, Shariat SF, Sidorenko VS, Fernandes A, Heguy A, Dickman KG, Olivier M, Grollman AP, Jelaković B, Zavadil J. Castells X, et al. Among authors: grollman ap. Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1873-81. doi: 10.1158/1055-9965.EPI-15-0553. Epub 2015 Sep 17. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 26383547 Free PMC article.
Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse.
Rosenquist TA, Einolf HJ, Dickman KG, Wang L, Smith A, Grollman AP. Rosenquist TA, et al. Among authors: grollman ap. Drug Metab Dispos. 2010 May;38(5):761-8. doi: 10.1124/dmd.110.032201. Epub 2010 Feb 17. Drug Metab Dispos. 2010. PMID: 20164109 Free PMC article.
Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid.
Jelaković B, Karanović S, Vuković-Lela I, Miller F, Edwards KL, Nikolić J, Tomić K, Slade N, Brdar B, Turesky RJ, Stipančić Ž, Dittrich D, Grollman AP, Dickman KG. Jelaković B, et al. Among authors: grollman ap. Kidney Int. 2012 Mar;81(6):559-67. doi: 10.1038/ki.2011.371. Epub 2011 Nov 9. Kidney Int. 2012. PMID: 22071594 Free PMC article.
Bioactivation of the human carcinogen aristolochic acid.
Sidorenko VS, Attaluri S, Zaitseva I, Iden CR, Dickman KG, Johnson F, Grollman AP. Sidorenko VS, et al. Among authors: grollman ap. Carcinogenesis. 2014 Aug;35(8):1814-22. doi: 10.1093/carcin/bgu095. Epub 2014 Apr 17. Carcinogenesis. 2014. PMID: 24743514 Free PMC article.
237 results