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Page 1
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I; Alzheimer Disease Genetics Consortium; St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R. Miyashita A, et al. Among authors: ikeda m. PLoS One. 2013;8(4):e58618. doi: 10.1371/journal.pone.0058618. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565137 Free PMC article.
Generation of amyloid beta protein from a presenilin-1 and betaAPP complex.
Shizuka-Ikeda M, Matsubara E, Ikeda M, Kanai M, Tomidokoro Y, Ikeda Y, Watanabe M, Kawarabayashi T, Harigaya Y, Okamoto K, Maruyama K, Castaño EM, St George-Hyslop P, Shoji M. Shizuka-Ikeda M, et al. Among authors: ikeda y, ikeda m. Biochem Biophys Res Commun. 2002 Mar 29;292(2):571-8. doi: 10.1006/bbrc.2002.6681. Biochem Biophys Res Commun. 2002. PMID: 11906199
Cerebrospinal fluid tau in dementia disorders: a large scale multicenter study by a Japanese study group.
Shoji M, Matsubara E, Murakami T, Manabe Y, Abe K, Kanai M, Ikeda M, Tomidokoro Y, Shizuka M, Watanabe M, Amari M, Ishiguro K, Kawarabayashi T, Harigaya Y, Okamoto K, Nishimura T, Nakamura Y, Takeda M, Urakami K, Adachi Y, Nakashima K, Arai H, Sasaki H, Kanemaru K, Yamanouchi H, Yoshida Y, Ichise K, Tanaka K, Hamamoto M, Yamamoto H, Matsubayashi T, Yoshida H, Toji H, Nakamura S, Hirai S. Shoji M, et al. Among authors: ikeda m. Neurobiol Aging. 2002 May-Jun;23(3):363-70. doi: 10.1016/s0197-4580(01)00309-8. Neurobiol Aging. 2002. PMID: 11959397
Decreased level of brain acetylcholine and memory disturbance in APPsw mice.
Ikarashi Y, Harigaya Y, Tomidokoro Y, Kanai M, Ikeda M, Matsubara E, Kawarabayashi T, Kuribara H, Younkin SG, Maruyama Y, Shoji M. Ikarashi Y, et al. Among authors: ikeda m. Neurobiol Aging. 2004 Apr;25(4):483-90. doi: 10.1016/S0197-4580(03)00122-2. Neurobiol Aging. 2004. PMID: 15013569
Soluble Abeta homeostasis in AD and DS: impairment of anti-amyloidogenic protection by lipoproteins.
Matsubara E, Sekijima Y, Tokuda T, Urakami K, Amari M, Shizuka-Ikeda M, Tomidokoro Y, Ikeda M, Kawarabayashi T, Harigaya Y, Ikeda S, Murakami T, Abe K, Otomo E, Hirai S, Frangione B, Ghiso J, Shoji M. Matsubara E, et al. Among authors: ikeda s, ikeda m. Neurobiol Aging. 2004 Aug;25(7):833-41. doi: 10.1016/j.neurobiolaging.2003.10.004. Neurobiol Aging. 2004. PMID: 15212837 Clinical Trial.
Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice.
Ikeda M, Shoji M, Kawarai T, Kawarabayashi T, Matsubara E, Murakami T, Sasaki A, Tomidokoro Y, Ikarashi Y, Kuribara H, Ishiguro K, Hasegawa M, Yen SH, Chishti MA, Harigaya Y, Abe K, Okamoto K, St George-Hyslop P, Westaway D. Ikeda M, et al. Am J Pathol. 2005 Feb;166(2):521-31. doi: 10.1016/S0002-9440(10)62274-2. Am J Pathol. 2005. PMID: 15681835 Free PMC article.
Type-specific evolution of amyloid plaque and angiopathy in APPsw mice.
Harigaya Y, Tomidokoro Y, Ikeda M, Sasaki A, Kawarabayashi T, Matsubara E, Kanai M, Saido TC, Younkin SG, Shoji M. Harigaya Y, et al. Among authors: ikeda m. Neurosci Lett. 2006 Feb 27;395(1):37-41. doi: 10.1016/j.neulet.2005.10.087. Epub 2005 Nov 18. Neurosci Lett. 2006. PMID: 16298484
Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-1.
Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K. Kurata T, et al. Among authors: ikeda m. J Neurosci Res. 2007 Aug 1;85(10):2246-52. doi: 10.1002/jnr.21352. J Neurosci Res. 2007. PMID: 17526016
6,534 results