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Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen.
Breast Cancer Res Treat. 2013 May;139(1):39-49. doi: 10.1007/s10549-013-2529-7. Epub 2013 Apr 17.
Breast Cancer Res Treat. 2013.
PMID: 23592373
Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen.
Jansen MP, Martens JW, Helmijr JC, Beaufort CM, van Marion R, Krol NM, Monkhorst K, Trapman-Jansen AM, Meijer-van Gelder ME, Weerts MJ, Ramirez-Ardila DE, Dubbink HJ, Foekens JA, Sleijfer S, Berns EM.
Jansen MP, et al. Among authors: ramirez ardila de.
Oncotarget. 2016 Jul 12;7(28):43412-43418. doi: 10.18632/oncotarget.9727.
Oncotarget. 2016.
PMID: 27270325
Free PMC article.
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LRG1 mRNA expression in breast cancer associates with PIK3CA genotype and with aromatase inhibitor therapy outcome.
Ramirez-Ardila DE, Ruigrok-Ritstier K, Helmijr JC, Look MP, van Laere S, Dirix L, Berns EM, Jansen MP.
Ramirez-Ardila DE, et al.
Mol Oncol. 2016 Oct;10(8):1363-73. doi: 10.1016/j.molonc.2016.07.004. Epub 2016 Jul 25.
Mol Oncol. 2016.
PMID: 27491861
Free PMC article.
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Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.
Jansen MP, Sas L, Sieuwerts AM, Van Cauwenberghe C, Ramirez-Ardila D, Look M, Ruigrok-Ritstier K, Finetti P, Bertucci F, Timmermans MM, van Deurzen CH, Martens JW, Simon I, Roepman P, Linn SC, van Dam P, Kok M, Lardon F, Vermeulen PB, Foekens JA, Dirix L, Berns EM, Van Laere S.
Jansen MP, et al.
Mol Oncol. 2015 Jun;9(6):1218-33. doi: 10.1016/j.molonc.2015.02.006. Epub 2015 Mar 4.
Mol Oncol. 2015.
PMID: 25771305
Free PMC article.
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Increased MAPK1/3 Phosphorylation in Luminal Breast Cancer Related with PIK3CA Hotspot Mutations and Prognosis.
Ramirez-Ardila D, Timmermans AM, Helmijr JA, Martens JWM, Berns EMJJ, Jansen MPHM.
Ramirez-Ardila D, et al.
Transl Oncol. 2017 Oct;10(5):854-866. doi: 10.1016/j.tranon.2017.08.002. Epub 2017 Sep 5.
Transl Oncol. 2017.
PMID: 28886403
Free PMC article.
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