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Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.
J Biol Chem. 2013 May 31;288(22):15687-98. doi: 10.1074/jbc.M112.431056. Epub 2013 Apr 23.
J Biol Chem. 2013.
PMID: 23612979
Free PMC article.
Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.
Babcock JT, Quilliam LA.
Babcock JT, et al.
Curr Drug Targets. 2011 Jul 1;12(8):1223-31. doi: 10.2174/138945011795906589.
Curr Drug Targets. 2011.
PMID: 21561413
Review.
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LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap.
Nguyen HB, Babcock JT, Wells CD, Quilliam LA.
Nguyen HB, et al. Among authors: babcock jt.
Oncogene. 2013 Aug 29;32(35):4100-9. doi: 10.1038/onc.2012.431. Epub 2012 Oct 1.
Oncogene. 2013.
PMID: 23027127
Free PMC article.
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Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
Siroky BJ, Yin H, Babcock JT, Lu L, Hellmann AR, Dixon BP, Quilliam LA, Bissler JJ.
Siroky BJ, et al. Among authors: babcock jt.
Am J Physiol Renal Physiol. 2012 Sep 15;303(6):F831-44. doi: 10.1152/ajprenal.00441.2011. Epub 2012 Jul 11.
Am J Physiol Renal Physiol. 2012.
PMID: 22791333
Free PMC article.
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M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.
Castro AF, Campos T, Babcock JT, Armijo ME, Martínez-Conde A, Pincheira R, Quilliam LA.
Castro AF, et al. Among authors: babcock jt.
J Cell Biochem. 2012 Apr;113(4):1253-64. doi: 10.1002/jcb.23458.
J Cell Biochem. 2012.
PMID: 22121046
Free PMC article.
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