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Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder.
Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Mehta D, et al. Among authors: altmann a. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8302-7. doi: 10.1073/pnas.1217750110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630272 Free PMC article.
vipR: variant identification in pooled DNA using R.
Altmann A, Weber P, Quast C, Rex-Haffner M, Binder EB, Müller-Myhsok B. Altmann A, et al. Bioinformatics. 2011 Jul 1;27(13):i77-84. doi: 10.1093/bioinformatics/btr205. Bioinformatics. 2011. PMID: 21685105 Free PMC article.
Performance of the methods was computed on SNPs that were also genotyped individually using a MALDI-TOF technique. On a set of 82 sequence variants, vipR achieved an average sensitivity of 0.80 at an average specificity of 0.92, thus outperforming the reference meth …
Performance of the methods was computed on SNPs that were also genotyped individually using a MALDI-TOF technique. On a set of …
Rare variants in TMEM132D in a case-control sample for panic disorder.
Quast C, Altmann A, Weber P, Arloth J, Bader D, Heck A, Pfister H, Müller-Myhsok B, Erhardt A, Binder EB. Quast C, et al. Among authors: altmann a. Am J Med Genet B Neuropsychiatr Genet. 2012 Dec;159B(8):896-907. doi: 10.1002/ajmg.b.32096. Epub 2012 Aug 22. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22911938
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.
Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC); Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC. Arloth J, et al. Among authors: altmann a. Neuron. 2015 Jun 3;86(5):1189-202. doi: 10.1016/j.neuron.2015.05.034. Neuron. 2015. PMID: 26050039 Free PMC article.
Functional coding variants in SLC6A15, a possible risk gene for major depression.
Quast C, Cuboni S, Bader D, Altmann A, Weber P, Arloth J, Röh S, Brückl T, Ising M, Kopczak A, Erhardt A, Hausch F, Lucae S, Binder EB. Quast C, et al. Among authors: altmann a. PLoS One. 2013 Jul 16;8(7):e68645. doi: 10.1371/journal.pone.0068645. Print 2013. PLoS One. 2013. PMID: 23874702 Free PMC article.
Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice.
Brenndörfer J, Altmann A, Widner-Andrä R, Pütz B, Czamara D, Tilch E, Kam-Thong T, Weber P, Rex-Haffner M, Bettecken T, Bultmann A, Müller-Myhsok B, Binder EE, Landgraf R, Czibere L. Brenndörfer J, et al. Among authors: altmann a. PLoS One. 2015 May 26;10(5):e0128465. doi: 10.1371/journal.pone.0128465. eCollection 2015. PLoS One. 2015. PMID: 26011321 Free PMC article.
A polymorphism in the Crhr1 gene determines stress vulnerability in male mice.
Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, Jones KA, Müller MB, Uhr M, Holsboer F, Binder EB, Schmidt MV. Labermaier C, et al. Among authors: altmann a. Endocrinology. 2014 Jul;155(7):2500-10. doi: 10.1210/en.2013-1986. Epub 2014 Apr 28. Endocrinology. 2014. PMID: 24773341
Cost-effective GPU-grid for genome-wide epistasis calculations.
Pütz B, Kam-Thong T, Karbalai N, Altmann A, Müller-Myhsok B. Pütz B, et al. Among authors: altmann a. Methods Inf Med. 2013;52(1):91-5. doi: 10.3414/ME11-02-0049. Epub 2012 Dec 7. Methods Inf Med. 2013. PMID: 23223640
GLIDE: GPU-based linear regression for detection of epistasis.
Kam-Thong T, Azencott CA, Cayton L, Pütz B, Altmann A, Karbalai N, Sämann PG, Schölkopf B, Müller-Myhsok B, Borgwardt KM. Kam-Thong T, et al. Among authors: altmann a. Hum Hered. 2012;73(4):220-36. doi: 10.1159/000341885. Epub 2012 Sep 4. Hum Hered. 2012. PMID: 22965145 Free article.
211 results