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Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.
Spivak-Kroizman TR, Hostetter G, Posner R, Aziz M, Hu C, Demeure MJ, Von Hoff D, Hingorani SR, Palculict TB, Izzo J, Kiriakova GM, Abdelmelek M, Bartholomeusz G, James BP, Powis G. Spivak-Kroizman TR, et al. Among authors: powis g. Cancer Res. 2013 Jun 1;73(11):3235-47. doi: 10.1158/0008-5472.CAN-11-1433. Epub 2013 Apr 30. Cancer Res. 2013. PMID: 23633488 Free PMC article.
HIF-1alpha and cancer therapy.
Koh MY, Spivak-Kroizman TR, Powis G. Koh MY, et al. Among authors: powis g. Recent Results Cancer Res. 2010;180:15-34. doi: 10.1007/978-3-540-78281-0_3. Recent Results Cancer Res. 2010. PMID: 20033376 Review.
HIF-1 regulation: not so easy come, easy go.
Yee Koh M, Spivak-Kroizman TR, Powis G. Yee Koh M, et al. Among authors: powis g. Trends Biochem Sci. 2008 Nov;33(11):526-34. doi: 10.1016/j.tibs.2008.08.002. Epub 2008 Sep 21. Trends Biochem Sci. 2008. PMID: 18809331 Review.
Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Grandjean G, de Jong PR, James B, Koh MY, Lemos R, Kingston J, Aleshin A, Bankston LA, Miller CP, Cho EJ, Edupuganti R, Devkota A, Stancu G, Liddington RC, Dalby K, Powis G. Grandjean G, et al. Among authors: powis g. Cancer Res. 2016 Jul 15;76(14):4259-4269. doi: 10.1158/0008-5472.CAN-16-0401. Epub 2016 Jun 3. Cancer Res. 2016. PMID: 27261507 Free PMC article.
363 results