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Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity.
Mobasher MA, González-Rodriguez A, Santamaría B, Ramos S, Martín MÁ, Goya L, Rada P, Letzig L, James LP, Cuadrado A, Martín-Pérez J, Simpson KJ, Muntané J, Valverde AM. Mobasher MA, et al. Among authors: simpson kj. Cell Death Dis. 2013 May 9;4(5):e626. doi: 10.1038/cddis.2013.150. Cell Death Dis. 2013. PMID: 23661004 Free PMC article.
SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress.
Rada P, Pardo V, Mobasher MA, García-Martínez I, Ruiz L, González-Rodríguez Á, Sanchez-Ramos C, Muntané J, Alemany S, James LP, Simpson KJ, Monsalve M, Valdecantos MP, Valverde ÁM. Rada P, et al. Among authors: simpson kj. Antioxid Redox Signal. 2018 May 1;28(13):1187-1208. doi: 10.1089/ars.2017.7373. Epub 2017 Dec 11. Antioxid Redox Signal. 2018. PMID: 29084443 Free PMC article.
miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma.
Holliday H, Yang J, Dodson E, Nikolic I, Kamili A, Wheatley M, Deng N, Alexandrou S, Davis TP, Kavallaris M, Caldon CE, McCarroll J, De Preter K, Mestdagh P, Marshall GM, Simpson KJ, Fletcher J, Swarbrick A. Holliday H, et al. Among authors: simpson kj. Mol Ther. 2024 May 16:S1525-0016(24)00310-1. doi: 10.1016/j.ymthe.2024.05.008. Online ahead of print. Mol Ther. 2024. PMID: 38759647 No abstract available.
Multimodal decoding of human liver regeneration.
Matchett KP, Wilson-Kanamori JR, Portman JR, Kapourani CA, Fercoq F, May S, Zajdel E, Beltran M, Sutherland EF, Mackey JBG, Brice M, Wilson GC, Wallace SJ, Kitto L, Younger NT, Dobie R, Mole DJ, Oniscu GC, Wigmore SJ, Ramachandran P, Vallejos CA, Carragher NO, Saeidinejad MM, Quaglia A, Jalan R, Simpson KJ, Kendall TJ, Rule JA, Lee WM, Hoare M, Weston CJ, Marioni JC, Teichmann SA, Bird TG, Carlin LM, Henderson NC. Matchett KP, et al. Among authors: simpson kj. Nature. 2024 Jun;630(8015):158-165. doi: 10.1038/s41586-024-07376-2. Epub 2024 May 1. Nature. 2024. PMID: 38693268
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network.
Lee RG, Rudler DL, Raven SA, Peng L, Chopin A, Moh ESX, McCubbin T, Siira SJ, Fagan SV, DeBono NJ, Stentenbach M, Browne J, Rackham FF, Li J, Simpson KJ, Marcellin E, Packer NH, Reid GE, Padman BS, Rackham O, Filipovska A. Lee RG, et al. Among authors: simpson kj. Nat Cell Biol. 2024 Jan;26(1):57-71. doi: 10.1038/s41556-023-01297-4. Epub 2023 Dec 21. Nat Cell Biol. 2024. PMID: 38129691
289 results