Crooks PA - Search Results

1

KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells.

Xu Y, Fang F, Miriyala S, Crooks PA, Oberley TD, Chaiswing L, Noel T, Holley AK, Zhao Y, Kiningham KK, Clair DK, Clair WH. Xu Y, et al. Among authors: crooks pa. Cancer Res. 2013 Jul 15;73(14):4406-17. doi: 10.1158/0008-5472.CAN-12-4297. Epub 2013 May 14. Cancer Res. 2013. PMID: 23674500 Free PMC article.

2

A NADPH oxidase-dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells.

Sun Y, St Clair DK, Xu Y, Crooks PA, St Clair WH. Sun Y, et al. Among authors: crooks pa. Cancer Res. 2010 Apr 1;70(7):2880-90. doi: 10.1158/0008-5472.CAN-09-4572. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233868 Free PMC article.

3

The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN.

Sun Y, St Clair DK, Fang F, Warren GW, Rangnekar VM, Crooks PA, St Clair WH. Sun Y, et al. Among authors: crooks pa. Mol Cancer Ther. 2007 Sep;6(9):2477-86. doi: 10.1158/1535-7163.MCT-07-0186. Mol Cancer Ther. 2007. PMID: 17876045 Free PMC article.

4

NADPH oxidase activity is essential for Keap1/Nrf2-mediated induction of GCLC in response to 2-indol-3-yl-methylenequinuclidin-3-ols.

Sekhar KR, Crooks PA, Sonar VN, Friedman DB, Chan JY, Meredith MJ, Starnes JH, Kelton KR, Summar SR, Sasi S, Freeman ML. Sekhar KR, et al. Among authors: crooks pa. Cancer Res. 2003 Sep 1;63(17):5636-45. Cancer Res. 2003. PMID: 14500406

5

The novel chemical entity YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppressing repair of DNA double-strand breaks and enhancing radiosensitization.

Sekhar KR, Reddy YT, Reddy PN, Crooks PA, Venkateswaran A, McDonald WH, Geng L, Sasi S, Van Der Waal RP, Roti JL, Salleng KJ, Rachakonda G, Freeman ML. Sekhar KR, et al. Among authors: crooks pa. Clin Cancer Res. 2011 Oct 15;17(20):6490-9. doi: 10.1158/1078-0432.CCR-11-1054. Epub 2011 Aug 30. Clin Cancer Res. 2011. PMID: 21878537 Free PMC article.

6

Novel chemical enhancers of heat shock increase thermal radiosensitization through a mitotic catastrophe pathway.

Sekhar KR, Sonar VN, Muthusamy V, Sasi S, Laszlo A, Sawani J, Horikoshi N, Higashikubo R, Bristow RG, Borrelli MJ, Crooks PA, Lepock JR, Roti Roti JL, Freeman ML. Sekhar KR, et al. Among authors: crooks pa. Cancer Res. 2007 Jan 15;67(2):695-701. doi: 10.1158/0008-5472.CAN-06-3212. Cancer Res. 2007. PMID: 17234780 Free article.

7

L-Canavanine as a radiosensitization agent for human pancreatic cancer cells.

Bence AK, Adams VR, Crooks PA. Bence AK, et al. Among authors: crooks pa. Mol Cell Biochem. 2003 Feb;244(1-2):37-43. Mol Cell Biochem. 2003. PMID: 12701807

8

The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development.

Venkateswaran A, Sekhar KR, Levic DS, Melville DB, Clark TA, Rybski WM, Walsh AJ, Skala MC, Crooks PA, Knapik EW, Freeman ML. Venkateswaran A, et al. Among authors: crooks pa. Cancer Res. 2014 Jan 1;74(1):38-43. doi: 10.1158/0008-5472.CAN-13-1981. Epub 2013 Nov 18. Cancer Res. 2014. PMID: 24247717 Free PMC article.

9

Melampomagnolide B: a new antileukemic sesquiterpene.

Nasim S, Pei S, Hagen FK, Jordan CT, Crooks PA. Nasim S, et al. Among authors: crooks pa. Bioorg Med Chem. 2011 Feb 15;19(4):1515-9. doi: 10.1016/j.bmc.2010.12.045. Epub 2011 Jan 6. Bioorg Med Chem. 2011. PMID: 21273084

10

DMAPT inhibits NF-κB activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivo.

Mendonca MS, Turchan WT, Alpuche ME, Watson CN, Estabrook NC, Chin-Sinex H, Shapiro JB, Imasuen-Williams IE, Rangel G, Gilley DP, Huda N, Crooks PA, Shapiro RH. Mendonca MS, et al. Among authors: crooks pa. Free Radic Biol Med. 2017 Nov;112:318-326. doi: 10.1016/j.freeradbiomed.2017.08.001. Epub 2017 Aug 3. Free Radic Biol Med. 2017. PMID: 28782644 Free PMC article.

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