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Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano G, Pikarsky E, Forshew T, Rosenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, Gorgoulis VG, Oren M. Cooks T, et al. Among authors: lozano g. Cancer Cell. 2013 May 13;23(5):634-46. doi: 10.1016/j.ccr.2013.03.022. Cancer Cell. 2013. PMID: 23680148 Free PMC article.
The loss of mdm2 induces p53-mediated apoptosis.
de Rozieres S, Maya R, Oren M, Lozano G. de Rozieres S, et al. Among authors: lozano g. Oncogene. 2000 Mar 23;19(13):1691-7. doi: 10.1038/sj.onc.1203468. Oncogene. 2000. PMID: 10763826
Mdm2-mediated ubiquitylation: p53 and beyond.
Marine JC, Lozano G. Marine JC, et al. Among authors: lozano g. Cell Death Differ. 2010 Jan;17(1):93-102. doi: 10.1038/cdd.2009.68. Cell Death Differ. 2010. PMID: 19498444 Review.
A Pin1/mutant p53 axis promotes aggressiveness in breast cancer.
Girardini JE, Napoli M, Piazza S, Rustighi A, Marotta C, Radaelli E, Capaci V, Jordan L, Quinlan P, Thompson A, Mano M, Rosato A, Crook T, Scanziani E, Means AR, Lozano G, Schneider C, Del Sal G. Girardini JE, et al. Among authors: lozano g. Cancer Cell. 2011 Jul 12;20(1):79-91. doi: 10.1016/j.ccr.2011.06.004. Cancer Cell. 2011. PMID: 21741598 Free article.
Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.
Xiong S, Tu H, Kollareddy M, Pant V, Li Q, Zhang Y, Jackson JG, Suh YA, Elizondo-Fraire AC, Yang P, Chau G, Tashakori M, Wasylishen AR, Ju Z, Solomon H, Rotter V, Liu B, El-Naggar AK, Donehower LA, Martinez LA, Lozano G. Xiong S, et al. Among authors: lozano g. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11145-50. doi: 10.1073/pnas.1404139111. Epub 2014 Jul 14. Proc Natl Acad Sci U S A. 2014. PMID: 25024203 Free PMC article.
501 results