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Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos.
Armant O, März M, Schmidt R, Ferg M, Diotel N, Ertzer R, Bryne JC, Yang L, Baader I, Reischl M, Legradi J, Mikut R, Stemple D, van IJcken W, van der Sloot A, Lenhard B, Strähle U, Rastegar S. Armant O, et al. Among authors: lenhard b. Dev Biol. 2013 Aug 15;380(2):351-62. doi: 10.1016/j.ydbio.2013.05.006. Epub 2013 May 14. Dev Biol. 2013. PMID: 23684812 Free PMC article.
Two independent transcription initiation codes overlap on vertebrate core promoters.
Haberle V, Li N, Hadzhiev Y, Plessy C, Previti C, Nepal C, Gehrig J, Dong X, Akalin A, Suzuki AM, van IJcken WFJ, Armant O, Ferg M, Strähle U, Carninci P, Müller F, Lenhard B. Haberle V, et al. Among authors: lenhard b. Nature. 2014 Mar 20;507(7492):381-385. doi: 10.1038/nature12974. Epub 2014 Feb 16. Nature. 2014. PMID: 24531765 Free PMC article.
Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome.
Naville M, Ishibashi M, Ferg M, Bengani H, Rinkwitz S, Krecsmarik M, Hawkins TA, Wilson SW, Manning E, Chilamakuri CS, Wilson DI, Louis A, Lucy Raymond F, Rastegar S, Strähle U, Lenhard B, Bally-Cuif L, van Heyningen V, FitzPatrick DR, Becker TS, Roest Crollius H. Naville M, et al. Among authors: lenhard b. Nat Commun. 2015 Apr 24;6:6904. doi: 10.1038/ncomms7904. Nat Commun. 2015. PMID: 25908307 Free PMC article.
A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells.
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F. van Riel B, et al. Among authors: lenhard b. Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16. Mol Cell Biol. 2012. PMID: 22801375 Free PMC article.
Dynamic regulation of the transcription initiation landscape at single nucleotide resolution during vertebrate embryogenesis.
Nepal C, Hadzhiev Y, Previti C, Haberle V, Li N, Takahashi H, Suzuki AM, Sheng Y, Abdelhamid RF, Anand S, Gehrig J, Akalin A, Kockx CE, van der Sloot AA, van Ijcken WF, Armant O, Rastegar S, Watson C, Strähle U, Stupka E, Carninci P, Lenhard B, Müller F. Nepal C, et al. Among authors: lenhard b. Genome Res. 2013 Nov;23(11):1938-50. doi: 10.1101/gr.153692.112. Epub 2013 Sep 3. Genome Res. 2013. PMID: 24002785 Free PMC article.
Transcriptional features of genomic regulatory blocks.
Akalin A, Fredman D, Arner E, Dong X, Bryne JC, Suzuki H, Daub CO, Hayashizaki Y, Lenhard B. Akalin A, et al. Among authors: lenhard b. Genome Biol. 2009;10(4):R38. doi: 10.1186/gb-2009-10-4-r38. Epub 2009 Apr 19. Genome Biol. 2009. PMID: 19374772 Free PMC article.
A cohesin-independent role for NIPBL at promoters provides insights in CdLS.
Zuin J, Franke V, van Ijcken WF, van der Sloot A, Krantz ID, van der Reijden MI, Nakato R, Lenhard B, Wendt KS. Zuin J, et al. Among authors: lenhard b. PLoS Genet. 2014 Feb 13;10(2):e1004153. doi: 10.1371/journal.pgen.1004153. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24550742 Free PMC article.
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.
Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, Demmers J, Rijkers EJ, Bhattacharya S, Philipsen S, Pevny LH, Grosveld FG, Rottier RJ, Lenhard B, Poot RA. Engelen E, et al. Among authors: lenhard b. Nat Genet. 2011 Jun;43(6):607-11. doi: 10.1038/ng.825. Epub 2011 May 1. Nat Genet. 2011. PMID: 21532573
187 results