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HDAC2 negatively regulates memory formation and synaptic plasticity.
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH. Guan JS, et al. Among authors: tsai lh. Nature. 2009 May 7;459(7243):55-60. doi: 10.1038/nature07925. Nature. 2009. PMID: 19424149 Free PMC article.
A novel pathway regulates memory and plasticity via SIRT1 and miR-134.
Gao J, Wang WY, Mao YW, Gräff J, Guan JS, Pan L, Mak G, Kim D, Su SC, Tsai LH. Gao J, et al. Among authors: tsai lh. Nature. 2010 Aug 26;466(7310):1105-9. doi: 10.1038/nature09271. Epub 2010 Jul 11. Nature. 2010. PMID: 20622856 Free PMC article.
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.
Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW. Schwer B, et al. Among authors: tsai lh. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21790-4. doi: 10.1073/pnas.1016306107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098266 Free PMC article.
Cognitive enhancement: A molecular memory booster.
Gräff J, Tsai LH. Gräff J, et al. Among authors: tsai lh. Nature. 2011 Jan 27;469(7331):474-5. doi: 10.1038/469474a. Nature. 2011. PMID: 21270879 No abstract available.
411 results