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Tumor-expressed adrenomedullin accelerates breast cancer bone metastasis.
Siclari VA, Mohammad KS, Tompkins DR, Davis H, McKenna CR, Peng X, Wessner LL, Niewolna M, Guise TA, Suvannasankha A, Chirgwin JM. Siclari VA, et al. Among authors: peng x. Breast Cancer Res. 2014 Dec 2;16(6):458. doi: 10.1186/s13058-014-0458-y. Breast Cancer Res. 2014. PMID: 25439669 Free PMC article.
Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.
Mohammad KS, Chen CG, Balooch G, Stebbins E, McKenna CR, Davis H, Niewolna M, Peng XH, Nguyen DH, Ionova-Martin SS, Bracey JW, Hogue WR, Wong DH, Ritchie RO, Suva LJ, Derynck R, Guise TA, Alliston T. Mohammad KS, et al. PLoS One. 2009;4(4):e5275. doi: 10.1371/journal.pone.0005275. Epub 2008 Apr 16. PLoS One. 2009. PMID: 19357790 Free PMC article.
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