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Ribosomal protein control of hematopoietic stem cell transformation through direct, non-canonical regulation of metabolism.
Harris B, Singh DK, Verma M, Fahl SP, Rhodes M, Sprinkle SR, Wang M, Zhang Y, Perrigoue J, Kessel R, Peri S, West J, Giricz O, Boultwood J, Pellagatti A, Ramesh KH, Montagna C, Pradhan K, Tyner JW, Kennedy BK, Holinstat M, Steidl U, Sykes S, Verma A, Wiest DL. Harris B, et al. Among authors: holinstat m. bioRxiv [Preprint]. 2023 Jun 1:2023.05.31.543132. doi: 10.1101/2023.05.31.543132. bioRxiv. 2023. PMID: 37398007 Free PMC article. Preprint.
Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design.
La CC, Smith SA, Vappala S, Adili R, Luke CE, Abbina S, Luo HD, Chafeeva I, Drayton M, Creagh LA, de Guadalupe Jaraquemada-Peláez M, Rhoads N, Kalathottukaren MT, Henke PK, Straus SK, Du C, Conway EM, Holinstat M, Haynes CA, Morrissey JH, Kizhakkedathu JN. La CC, et al. Among authors: holinstat m. Nat Commun. 2023 Apr 26;14(1):2177. doi: 10.1038/s41467-023-37709-0. Nat Commun. 2023. PMID: 37100783 Free PMC article.
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.
Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB 2nd, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, Holman TR. Kenyon V, et al. Among authors: holinstat m. J Med Chem. 2011 Aug 11;54(15):5485-97. doi: 10.1021/jm2005089. Epub 2011 Jul 8. J Med Chem. 2011. PMID: 21739938 Free PMC article.
107 results