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Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.
Yeung J, Tourdot BE, Fernandez-Perez P, Vesci J, Ren J, Smyrniotis CJ, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, McKenzie SE, Holinstat M. Yeung J, et al. Among authors: vesci j. Blood. 2014 Oct 2;124(14):2271-9. doi: 10.1182/blood-2014-05-575878. Epub 2014 Aug 6. Blood. 2014. PMID: 25100742 Free PMC article.
The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y12 inhibition.
Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF. Whitley MJ, et al. Among authors: vesci j. J Thromb Haemost. 2018 Dec;16(12):2501-2514. doi: 10.1111/jth.14318. Epub 2018 Nov 22. J Thromb Haemost. 2018. PMID: 30347494 Free PMC article.
Platelet concentrate effects on thromboelastography.
McNulty SE, Sasso P, Vesci J, Schieren H. McNulty SE, et al. Among authors: vesci j. J Cardiothorac Vasc Anesth. 1997 Dec;11(7):828-30. doi: 10.1016/s1053-0770(97)90114-2. J Cardiothorac Vasc Anesth. 1997. PMID: 9412878