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Selective cannabinoid receptor type 2 (CB2) agonists: optimization of a series of purines leading to the identification of a clinical candidate for the treatment of osteoarthritic pain.
Hollinshead SP, Tidwell MW, Palmer J, Guidetti R, Sanderson A, Johnson MP, Chambers MG, Oskins J, Stratford R, Astles PC. Hollinshead SP, et al. Among authors: tidwell mw. J Med Chem. 2013 Jul 25;56(14):5722-33. doi: 10.1021/jm400305d. Epub 2013 Jul 3. J Med Chem. 2013. PMID: 23795771
Design, synthesis, and characterization of novel, nonquaternary reactivators of GF-inhibited human acetylcholinesterase.
McHardy SF, Bohmann JA, Corbett MR, Campos B, Tidwell MW, Thompson PM, Bemben CJ, Menchaca TA, Reeves TE, Cantrell WR Jr, Bauta WE, Lopez A, Maxwell DM, Brecht KM, Sweeney RE, McDonough J. McHardy SF, et al. Among authors: tidwell mw. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1711-4. doi: 10.1016/j.bmcl.2014.02.049. Epub 2014 Feb 28. Bioorg Med Chem Lett. 2014. PMID: 24630558