Bromberg J - Search Results

1

The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.

Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SP, Daly L, Wels J, Theilen T, Granitto S, Zhang X, Cotari J, Alpaugh ML, de Stanchina E, Manova K, Li M, Bonafe M, Ceccarelli C, Taffurelli M, Santini D, Altan-Bonnet G, Kaplan R, Norton L, Nishimoto N, Huszar D, Lyden D, Bromberg J. Chang Q, et al. Among authors: bromberg j. Neoplasia. 2013 Jul;15(7):848-62. doi: 10.1593/neo.13706. Neoplasia. 2013. PMID: 23814496 Free PMC article.

2

Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C.

Dechow TN, Pedranzini L, Leitch A, Leslie K, Gerald WL, Linkov I, Bromberg JF. Dechow TN, et al. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10602-7. doi: 10.1073/pnas.0404100101. Epub 2004 Jul 12. Proc Natl Acad Sci U S A. 2004. PMID: 15249664 Free PMC article.

3

Stat3 is required for the development of skin cancer.

Pedranzini L, Leitch A, Bromberg J. Pedranzini L, et al. Among authors: bromberg j. J Clin Invest. 2004 Sep;114(5):619-22. doi: 10.1172/JCI22800. J Clin Invest. 2004. PMID: 15343379 Free PMC article.

4

Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3.

Leslie K, Lang C, Devgan G, Azare J, Berishaj M, Gerald W, Kim YB, Paz K, Darnell JE, Albanese C, Sakamaki T, Pestell R, Bromberg J. Leslie K, et al. Among authors: bromberg j. Cancer Res. 2006 Mar 1;66(5):2544-52. doi: 10.1158/0008-5472.CAN-05-2203. Cancer Res. 2006. PMID: 16510571

5

Touched and moved by STAT3.

Gao SP, Bromberg JF. Gao SP, et al. Sci STKE. 2006 Jul 11;2006(343):pe30. doi: 10.1126/stke.3432006pe30. Sci STKE. 2006. PMID: 16835434 Review.

6

Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.

Pedranzini L, Dechow T, Berishaj M, Comenzo R, Zhou P, Azare J, Bornmann W, Bromberg J. Pedranzini L, et al. Among authors: bromberg j. Cancer Res. 2006 Oct 1;66(19):9714-21. doi: 10.1158/0008-5472.CAN-05-4280. Cancer Res. 2006. PMID: 17018630

7

Increased dose density is feasible: a pilot study of adjuvant epirubicin and cyclophosphamide followed by paclitaxel, at 10- or 11-day intervals with filgrastim support in women with breast cancer.

Fornier MN, Seidman AD, Lake D, D'Andrea G, Bromberg J, Robson M, Van Poznak C, Panageas KS, Atienza M, Norton L, Hudis C. Fornier MN, et al. Among authors: bromberg j. Clin Cancer Res. 2007 Jan 1;13(1):223-7. doi: 10.1158/1078-0432.CCR-06-1731. Clin Cancer Res. 2007. PMID: 17200358 Clinical Trial.

8

Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6.

Azare J, Leslie K, Al-Ahmadie H, Gerald W, Weinreb PH, Violette SM, Bromberg J. Azare J, et al. Among authors: bromberg j. Mol Cell Biol. 2007 Jun;27(12):4444-53. doi: 10.1128/MCB.02404-06. Epub 2007 Apr 16. Mol Cell Biol. 2007. PMID: 17438134 Free PMC article.

9

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

Berishaj M, Gao SP, Ahmed S, Leslie K, Al-Ahmadie H, Gerald WL, Bornmann W, Bromberg JF. Berishaj M, et al. Breast Cancer Res. 2007;9(3):R32. doi: 10.1186/bcr1680. Breast Cancer Res. 2007. PMID: 17531096 Free PMC article.

10

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Gao SP, Mark KG, Leslie K, Pao W, Motoi N, Gerald WL, Travis WD, Bornmann W, Veach D, Clarkson B, Bromberg JF. Gao SP, et al. J Clin Invest. 2007 Dec;117(12):3846-56. doi: 10.1172/JCI31871. J Clin Invest. 2007. PMID: 18060032 Free PMC article.

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