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The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.
Neoplasia. 2013 Jul;15(7):848-62. doi: 10.1593/neo.13706.
Neoplasia. 2013.
PMID: 23814496
Free PMC article.
Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.
Cotari JW, Voisinne G, Dar OE, Karabacak V, Altan-Bonnet G.
Cotari JW, et al.
Sci Signal. 2013 Mar 12;6(266):ra17. doi: 10.1126/scisignal.2003240.
Sci Signal. 2013.
PMID: 23482665
Free PMC article.
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Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death.
Cotari JW, Voisinne G, Altan-Bonnet G.
Cotari JW, et al.
Curr Opin Biotechnol. 2013 Aug;24(4):760-6. doi: 10.1016/j.copbio.2013.05.002. Epub 2013 Jun 7.
Curr Opin Biotechnol. 2013.
PMID: 23747193
Free PMC article.
Review.
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EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines.
Chakravarty D, Pedraza AM, Cotari J, Liu AH, Punko D, Kokroo A, Huse JT, Altan-Bonnet G, Brennan CW.
Chakravarty D, et al. Among authors: cotari j.
Sci Rep. 2017 Aug 22;7(1):9043. doi: 10.1038/s41598-017-08940-9.
Sci Rep. 2017.
PMID: 28831081
Free PMC article.
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Human Langerhans cells use an IL-15R-α/IL-15/pSTAT5-dependent mechanism to break T-cell tolerance against the self-differentiation tumor antigen WT1.
Romano E, Cotari JW, Barreira da Silva R, Betts BC, Chung DJ, Avogadri F, Fink MJ, St Angelo ET, Mehrara B, Heller G, Münz C, Altan-Bonnet G, Young JW.
Romano E, et al. Among authors: cotari jw.
Blood. 2012 May 31;119(22):5182-90. doi: 10.1182/blood-2011-09-382200. Epub 2012 Apr 17.
Blood. 2012.
PMID: 22510877
Free PMC article.
Clinical Trial.
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T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.
Tkach KE, Barik D, Voisinne G, Malandro N, Hathorn MM, Cotari JW, Vogel R, Merghoub T, Wolchok J, Krichevsky O, Altan-Bonnet G.
Tkach KE, et al. Among authors: cotari jw.
Elife. 2014 Apr 9;3:e01944. doi: 10.7554/eLife.01944.
Elife. 2014.
PMID: 24719192
Free PMC article.
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Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.
Palomba ML, Piersanti K, Ziegler CG, Decker H, Cotari JW, Bantilan K, Rijo I, Gardner JR, Heaney M, Bemis D, Balderas R, Malek SN, Seymour E, Zelenetz AD, van den Brink MR, Altan-Bonnet G.
Palomba ML, et al. Among authors: cotari jw.
PLoS One. 2014 Jan 29;9(1):e79987. doi: 10.1371/journal.pone.0079987. eCollection 2014.
PLoS One. 2014.
PMID: 24489640
Free PMC article.
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