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The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis.
Chang Q, Bournazou E, Sansone P, Berishaj M, Gao SP, Daly L, Wels J, Theilen T, Granitto S, Zhang X, Cotari J, Alpaugh ML, de Stanchina E, Manova K, Li M, Bonafe M, Ceccarelli C, Taffurelli M, Santini D, Altan-Bonnet G, Kaplan R, Norton L, Nishimoto N, Huszar D, Lyden D, Bromberg J. Chang Q, et al. Among authors: lyden d. Neoplasia. 2013 Jul;15(7):848-62. doi: 10.1593/neo.13706. Neoplasia. 2013. PMID: 23814496 Free PMC article.
Preparing the "soil": the premetastatic niche.
Kaplan RN, Rafii S, Lyden D. Kaplan RN, et al. Among authors: lyden d. Cancer Res. 2006 Dec 1;66(23):11089-93. doi: 10.1158/0008-5472.CAN-06-2407. Cancer Res. 2006. PMID: 17145848 Free PMC article. Review.
Niche-to-niche migration of bone-marrow-derived cells.
Kaplan RN, Psaila B, Lyden D. Kaplan RN, et al. Among authors: lyden d. Trends Mol Med. 2007 Feb;13(2):72-81. doi: 10.1016/j.molmed.2006.12.003. Epub 2007 Jan 2. Trends Mol Med. 2007. PMID: 17197241 Review.
Stat3 mediates expression of autotaxin in breast cancer.
Azare J, Doane A, Leslie K, Chang Q, Berishaj M, Nnoli J, Mark K, Al-Ahmadie H, Gerald W, Hassimi M, Viale A, Stracke M, Lyden D, Bromberg J. Azare J, et al. Among authors: lyden d. PLoS One. 2011;6(11):e27851. doi: 10.1371/journal.pone.0027851. Epub 2011 Nov 28. PLoS One. 2011. PMID: 22140473 Free PMC article.
147 results