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Discovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapy.
PLoS One. 2013 Jun 24;8(6):e65928. doi: 10.1371/journal.pone.0065928. Print 2013.
PLoS One. 2013.
PMID: 23826084
Free PMC article.
Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa.
Warrilow AG, Price CL, Parker JE, Rolley NJ, Smyrniotis CJ, Hughes DD, Thoss V, Nes WD, Kelly DE, Holman TR, Kelly SL.
Warrilow AG, et al. Among authors: smyrniotis cj.
Sci Rep. 2016 Jun 13;6:27690. doi: 10.1038/srep27690.
Sci Rep. 2016.
PMID: 27291783
Free PMC article.
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ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid.
Smyrniotis CJ, Barbour SR, Xia Z, Hixon MS, Holman TR.
Smyrniotis CJ, et al.
Biochemistry. 2014 Jul 15;53(27):4407-19. doi: 10.1021/bi401621d. Epub 2014 Jul 2.
Biochemistry. 2014.
PMID: 24893149
Free PMC article.
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Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.
Yeung J, Tourdot BE, Fernandez-Perez P, Vesci J, Ren J, Smyrniotis CJ, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, McKenzie SE, Holinstat M.
Yeung J, et al. Among authors: smyrniotis cj.
Blood. 2014 Oct 2;124(14):2271-9. doi: 10.1182/blood-2014-05-575878. Epub 2014 Aug 6.
Blood. 2014.
PMID: 25100742
Free PMC article.
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Metabolic labeling of sialic acids in living animals with alkynyl sugars.
Chang PV, Chen X, Smyrniotis C, Xenakis A, Hu T, Bertozzi CR, Wu P.
Chang PV, et al.
Angew Chem Int Ed Engl. 2009;48(22):4030-3. doi: 10.1002/anie.200806319.
Angew Chem Int Ed Engl. 2009.
PMID: 19388017
Free PMC article.
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