Gakhar L - Search Results

1

High-resolution structure of the Tiam1 PHn-CC-Ex domain.

Joshi M, Gakhar L, Fuentes EJ. Joshi M, et al. Among authors: gakhar l. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jul;69(Pt 7):744-52. doi: 10.1107/S1744309113014206. Epub 2013 Jun 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23832200 Free PMC article.

2

A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.

Freudenthal BD, Gakhar L, Ramaswamy S, Washington MT. Freudenthal BD, et al. Among authors: gakhar l. Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):560-6. doi: 10.1107/S0907444909011329. Epub 2009 May 15. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19465770 Free PMC article.

3

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.

Freudenthal BD, Gakhar L, Ramaswamy S, Washington MT. Freudenthal BD, et al. Among authors: gakhar l. Nat Struct Mol Biol. 2010 Apr;17(4):479-84. doi: 10.1038/nsmb.1776. Epub 2010 Mar 21. Nat Struct Mol Biol. 2010. PMID: 20305653 Free PMC article.

4

The structure of LsrB from Yersinia pestis complexed with autoinducer-2.

Kavanaugh JS, Gakhar L, Horswill AR. Kavanaugh JS, et al. Among authors: gakhar l. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1501-5. doi: 10.1107/S1744309111042953. Epub 2011 Nov 29. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22139152 Free PMC article.

5

Structure and functional analysis of the BRCT domain of translesion synthesis DNA polymerase Rev1.

Pryor JM, Gakhar L, Washington MT. Pryor JM, et al. Among authors: gakhar l. Biochemistry. 2013 Jan 8;52(1):254-63. doi: 10.1021/bi301572z. Epub 2012 Dec 20. Biochemistry. 2013. PMID: 23240687 Free PMC article.

6

Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains.

Gakhar L, Bassuk AG, Velez G, Khan S, Yang J, Tsang SH, Mahajan VB. Gakhar L, et al. J Struct Biol. 2016 Dec;196(3):309-318. doi: 10.1016/j.jsb.2016.07.017. Epub 2016 Jul 27. J Struct Biol. 2016. PMID: 27474374 Free PMC article.

7

Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.

Liu X, Speckhard DC, Shepherd TR, Sun YJ, Hengel SR, Yu L, Fowler CA, Gakhar L, Fuentes EJ. Liu X, et al. Among authors: gakhar l. Structure. 2016 Dec 6;24(12):2053-2066. doi: 10.1016/j.str.2016.08.019. Epub 2016 Oct 27. Structure. 2016. PMID: 27998539 Free PMC article.

8

The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.

Xu Z, Gakhar L, Bain FE, Spies M, Fuentes EJ. Xu Z, et al. Among authors: gakhar l. J Biol Chem. 2017 Oct 27;292(43):17777-17793. doi: 10.1074/jbc.M117.799114. Epub 2017 Sep 7. J Biol Chem. 2017. PMID: 28882897 Free PMC article.

9

Structural underpinnings of Ric8A function as a G-protein α-subunit chaperone and guanine-nucleotide exchange factor.

Srivastava D, Gakhar L, Artemyev NO. Srivastava D, et al. Among authors: gakhar l. Nat Commun. 2019 Jul 12;10(1):3084. doi: 10.1038/s41467-019-11088-x. Nat Commun. 2019. PMID: 31300652 Free PMC article.

10

Dependence of crystallographic atomic displacement parameters on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenase.

Plapp BV, Gakhar L, Subramanian R. Plapp BV, et al. Among authors: gakhar l. Acta Crystallogr D Struct Biol. 2022 Oct 1;78(Pt 10):1221-1234. doi: 10.1107/S2059798322008361. Epub 2022 Sep 27. Acta Crystallogr D Struct Biol. 2022. PMID: 36189742 Free PMC article.

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